---
scientific_name: Glycine max
gene_symbols:
  - GmNNL1
gene_symbol_long: Nodule Number Locus 1
gene_model_pub_name: Glyma.02G076900
gene_model_full_id: glyma.Wm82.gnm2.ann1.Glyma.02G076900
confidence: 5
curators:
  - Marlene Dorneich-Hayes
comments:
  - NNL1 encodes an R protein that interacts with nodulation outer protein P (NopP) of Bradyrhizobium japonicum to prevent symbiosis.
  - Different NNL1 alleles provide immunity to different B. japonicum symbionts.
  - GmSINE1 may be inserted into NNL1, producing an inactive truncated protein. Infection proceeds normally when NNL1 is nonfunctional.
  - NNL1 is induced by innoculation with B. japonicum and expressed in root hairs.
phenotype_synopsis: NNL1 gives soy plants immunity to root hair infection by B. japonicum, which inhibits nodulation and reduces nitrogen fixation.
traits:
  - entity_name: regulation of biological process involved in symbiotic interaction
    entity: GO:0043903
  - entity_name: nodulation
    entity: GO:0009877
  - relation_name: negatively regulates
    entity: RO:0002212
references:
  - citation: Zhang, Wang et. al, 2021
    doi: 10.1038/s41477-020-00832-7
    pmid: 33452487
  - citation: Yang, Lan et. al., 2022
    doi: 10.1111/jipb.13207
    pmid: 34962095
---
scientific_name: Glycine max
gene_symbols:
  - GmRj2
gene_symbol_long: Resistance j2
gene_model_pub_name: Glyma16g33780
gene_model_full_id: glyma.Wm82.gnm2.ann1.Glyma.16G33780
confidence: 5
curators:
  - Marlene Dorneich-Hayes
comments:
  - Rj2 interacts with rhizobial NopP to determine compatibility of infecting rhizobia.
  - Different Rj2 alleles provide immunity to different Bradyrhizobium symbionts.
  - When invading NopP is incompatible with host Rj2, Rj2 activates defence gene PR-2 to prevent infection.
  - Regardless of rhizobial compatibility, Rj2 induces ENOD40.
  - Rj2 is expressed in nodules, root hairs, root tips, and shoot meristems.
phenotype_synopsis: Rj2 is a resistance gene involved in sensing compatibility between soy and Bradyrhizobium symbionts.
traits:
  - entity_name: regulation of biological process involved in symbiotic interaction
    entity: GO:0043903
  - entity_name: nodulation
    entity: GO:0009877
  - relation_name: negatively regulates
    entity: RO:0002212
references:
  - citation: Zhang, Wang et. al, 2021
    doi: 10.1038/s41477-020-00832-7
    pmid: 33452487
  - citation: Sugawara, Takahashi et. al., 2018
    doi: 10.1038/s41467-018-05663-x
    pmid: 30087346
  - citation: Sugawara, Umehara et al., 2019
    doi: 10.1371/journal.pone.0222469
    pmid: 31518373
  - citation: Yang, Lan et. al., 2022
    doi: 10.1111/jipb.13207
    pmid: 34962095