---
scientific_name: Glycine max
gene_symbols:
  - GmNARK
gene_symbol_long: Nodule Autoregulation Receptor Kinase
gene_model_pub_name: Glyma.12G040000
gene_model_full_id: glyma.Wm82.gnm2.ann1.Glyma.12G040000
confidence: 4
curators:
  - Marlene Dorneich-Hayes
  - Scott Kalberer
comments:
  - All these studies identified the implicated gene by comparing mutant strains to each other and to wild type.
  - GmNARK is a negative regulator of miR172c, which affects the activity of nodulation gene GmNNC1 (see Wang, Wang et al., 2014).
  - NARK is expressed in roots, leaves, and shoots.
  - If the kinase domain of NARK is nonfunctional, most plants produce huge numbers of extra nodules, extra lateral roots, and more symbiotic interactions.
  - If NARK is less severely compromised, fewer extra nodules form.
phenotype_synopsis: GmNARK exerts long-distance control on nodule proliferation by activating nodulation-suppressing genes.
traits:
  - entity_name: kinase activity
    entity: GO:0016301
  - entity_name: regulation of biological process involved in symbiotic interaction
    entity: GO:0043903
  - entity_name: nodulation
    entity: GO:0009877
  - entity_name: root development
    entity: GO:0048364
references:
  - citation: Searle, Men et al., 2003
    doi: 10.1126/science.1077937
    pmid: 12411574
  - citation: Kim, Van et al., 2005
    doi: 10.1007/s00122-004-1887-2
    pmid: 15731930
  - citation: Meixner, Vegvari et al., 2007
    doi: 10.1111/j.1399-3054.2007.00903.x
    pmid: null
  - citation: Wang, Wang et al., 2014
    doi: 10.1105/tpc.114.131607
    pmid: 25549672
  - citation: Yang, Lan et al., 2022
    doi: 10.1111/jipb.13207
    pmid: 34962095