--- scientific_name: Glycine max gene_symbols: - GmMIPS gene_symbol_long: Myo-Inositol-Phosphate Synthase gene_model_pub_name: Glyma.11G238800 gene_model_full_id: glyma.Wm82.gnm2.ann1.Glyma.11G238800 confidence: 3 curators: - Marlene Dorneich-Hayes - Scott Kalberer comments: - Silencing of GmMIPS in transgenic lines (with RNAi and antisense) reduces accumulation of phytic acid in seeds. phenotype_synopsis: GmMIPS codes for the rate-limiting enzyme in phytic acid biosynthesis. Supression of MIPS reduces the phytic acid concentration in seeds which improves their nutritional value, but also reduces their germination rate. traits: - entity_name: biosynthetic process entity: GO:0009058 references: - citation: Redekar, Glover et al., 2020 doi: 10.1371/journal.pone.0235120 pmid: 32584851 - citation: Kumar, Kumar et al., 2019 doi: 10.1038/s41598-019-44255-7 pmid: 31123331 - citation: Yu, Jin et al., 2019 doi: 10.1186/s12870-019-2201-4 pmid: 31856712 - citation: Nunes, Vianna et al., 2006 doi: 10.1007/s00425-005-0201-0 pmid: 16395584 - citation: Hegeman, Good et al., 2001 doi: 10.1104/pp.125.4.1941 pmid: 11299373