---
scientific_name: Glycine max
gene_symbols:
  - GmFAD2-1A
gene_symbol_long: Fatty Acid Desaturase 2-1A
gene_model_pub_name: Glyma.10G278000
gene_model_full_id: glyma.Wm82.gnm2.ann1.Glyma.10G278000
confidence: 4
curators:
  - Marlene Dorneich-Hayes
  - Scott Kalberer
comments:
  - If GmFAD2-1A and GmFAD2-1B are both downregulated or have loss-of-function mutations, seeds will have high oleic acid content.
  - Knockout studies confirm that functional FAD2-1A decreases accumulation of oleic acid in seeds.
phenotype_synopsis: GmFAD2-1A converts the precursors of oleic acid into linoleic acid.
traits:
  - entity_name: lipid metabolic process
    entity: GO:0006629
  - entity_name: regulation of triglyceride biosynthetic process
    entity: GO:0010866
  - entity_name: fat and essential oil content
    entity: TO:0000604
references:
  - citation: Pham, Lee et al., 2010
    doi: 10.1186/1471-2229-10-195
    pmid: 20828382
  - citation: Combs, Bilyeu, 2019
    doi: 10.1007/s11032-019-0972-9
    pmid: null
  - citation: Zuo, Ikram et al., 2022
    doi: 10.1016/j.csbj.2022.06.014
    pmid: 35782726
---
scientific_name: Glycine max
gene_symbols:
  - GmFAD2-1B
gene_symbol_long: Fatty Acid Desaturase 2-1B
gene_model_pub_name: Glyma.20G111000
gene_model_full_id: glyma.Wm82.gnm4.ann1.Glyma.20G111000
confidence: 4
curators:
  - Marlene Dorneich-Hayes
  - Scott Kalberer
comments:
  - If GmFAD2-1A and GmFAD2-1B are both downregulated or have loss-of-function mutations, seeds will have high oleic acid content.
  - FAD2-1B is more active at low temperatures.
  - Knockout studies confirm that functional FAD2-1B decreases accumulation of oleic acid in seeds.
phenotype_synopsis: Normal GmFAD2-1B converts the precursors of oleic acid into linoleic acid.
traits:
  - entity_name: lipid metabolic process
    entity: GO:0006629
  - entity_name: regulation of triglyceride biosynthetic process
    entity: GO:0010866
  - entity_name: fat and essential oil content
    entity: TO:0000604
references:
  - citation: Pham, Lee et al., 2010
    doi: 10.1186/1471-2229-10-195
    pmid: 20828382
  - citation: Combs, Bilyeu, 2019
    doi: 10.1007/s11032-019-0972-9
    pmid: null