---
scientific_name: Glycine max
gene_symbols:
  - GmABCC8
gene_symbol_long: ATP-Binding Cassette Transporter 8
gene_model_pub_name: Glyma.07G011600
gene_model_full_id: glyma.Wm82.gnm2.ann1.Glyma.07G011600
confidence: 5
curators:
  - Marlene Dorneich-Hayes
  - Scott Kalberer
comments:
  - Overexpression of GmABCC8 in transgenic plants created glyphosate resistance. ABCC8 knockout plants had decreased resistance to glyphosate.
phenotype_synopsis: GmABCC8 codes for an efflux pump that extrudes the herbicide glyphosate out of a cell's cytoplasm, making the plant glyphosate resistant.
traits:
  - entity_name: glyphosate sensitivity
    entity: TO:0005006
  - entity_name: herbicide resistance
    entity: OMIT:0025284
  - entity_name: ABC-type transporter activity
    entity: GO:0140359
references:
  - citation: Pan, Yu et al., 2021
    doi: 10.1073/pnas.2100136118
    pmid: 33846264