---
scientific_name: Glycine max
gene_symbols:
  - GmDMI1-3
gene_symbol_long: Doesn't Make Infections 1-3
gene_model_pub_name: Glyma.19G263500
gene_model_full_id: glyma.Wm82.gnm2.ann1.Glyma.19G263500
confidence: 4
curators:
  - Marlene Dorneich-Hayes
  - Scott Kalberer
comments:
  - Transgenic overexpression of DMI1 reduces Heterodera glycines parasitism and increases nodulation. RNAi silencing of DMI1 increases suceptibility to H. glycines and reduces nodulation.
phenotype_synopsis: DMI genes confer resistance to H. glycines nematodes and are necessary for establishing symbiosis. DMI1 encodes a channel protein that controls the signalling pathway leading to nodulation.
traits:
  - entity_name: biological process involved in symbiotic interaction
    entity: GO:0044403
  - entity_name: nodulation
    entity: GO:0009877
  - entity_name: defense response to nematode
    entity: GO:0002215
references:
  - citation: Khatri, Pant et al., 2022
    doi: 10.3389/fpls.2022.842597
    pmid: 35599880
---
scientific_name: Glycine max
gene_symbols:
  - GmDMI2-7
gene_symbol_long: Doesn't Make Infections 2-7
gene_model_pub_name: Glyma.11G246200
gene_model_full_id: glyma.Wm82.gnm2.ann1.Glyma.11G246200
confidence: 4
curators:
  - Marlene Dorneich-Hayes
  - Scott Kalberer
comments:
  - Transgenic overexpression of DMI2 reduces Heterodera glycines parasitism and increases nodulation even without rhizobia. RNAi silencing of DMI2 increases suceptibility to H. glycines and reduces nodulation.
phenotype_synopsis: DMI genes confer resistance to H. glycines nematodes and are necessary for establishing symbiosis. DMI2 encodes a kinase.
traits:
  - entity_name: biological process involved in symbiotic interaction
    entity: GO:0044403
  - entity_name: nodulation
    entity: GO:0009877
  - entity_name: defense response to nematode
    entity: GO:0002215
  - entity_name: protein kinase activity
    entity: GO:0004672
references:
  - citation: Khatri, Pant et al., 2022
    doi: 10.3389/fpls.2022.842597
    pmid: 35599880
---
scientific_name: Glycine max
gene_symbols:
  - GmDMI3-2
gene_symbol_long: Doesn't Make Infections 3-2
gene_model_pub_name: Glyma.15G222300
gene_model_full_id: glyma.Wm82.gnm2.ann1.Glyma.15G222300
confidence: 4
curators:
  - Marlene Dorneich-Hayes
  - Scott Kalberer
comments:
  - Transgenic overexpression of DMI3 reduces Heterodera glycines parasitism and increases nodulation even without rhizobia. RNAi silencing of DMI3 increases suceptibility to H. glycines and reduces nodulation.
phenotype_synopsis: DMI genes confer resistance to H. glycines nematodes and are necessary for establishing symbiosis. DMI3 encodes a kinase.
traits:
  - entity_name: biological process involved in symbiotic interaction
    entity: GO:0044403
  - entity_name: nodulation
    entity: GO:0009877
  - entity_name: defense response to nematode
    entity: GO:0002215
  - entity_name: protein kinase activity
    entity: GO:0004672
references:
  - citation: Khatri, Pant et al., 2022
    doi: 10.3389/fpls.2022.842597
    pmid: 35599880