##### PUB RECORD #####
## 10.1105/tpc.105.035394 16199614 PMC1276019 Ivashuta, Liu, et al., 2005 "Ivashuta S, Liu J, Liu J, Lohar DP, Haridas S, Bucciarelli B, VandenBosch KA, Vance CP, Harrison MJ, Gantt JS. RNA interference identifies a calcium-dependent protein kinase involved in Medicago truncatula root development. Plant Cell. 2005 Nov;17(11):2911-21. doi: 10.1105/tpc.105.035394. Epub 2005 Sep 30. PMID: 16199614; PMCID: PMC1276019." ##
PMID- 16199614
OWN - NLM
STAT- MEDLINE
DCOM- 20060526
LR - 20220408
IS - 1040-4651 (Print)
IS - 1532-298X (Electronic)
IS - 1040-4651 (Linking)
VI - 17
IP - 11
DP - 2005 Nov
TI - RNA interference identifies a calcium-dependent protein kinase involved in
Medicago truncatula root development.
PG - 2911-21
AB - Changes in cellular or subcellular Ca2+ concentrations play essential roles in
plant development and in the responses of plants to their environment. However,
the mechanisms through which Ca2+ acts, the downstream signaling components, as
well as the relationships among the various Ca2+-dependent processes remain
largely unknown. Using an RNA interference-based screen for gene function in
Medicago truncatula, we identified a gene that is involved in root development.
Silencing Ca2+-dependent protein kinase1 (CDPK1), which is predicted to encode a
Ca2+-dependent protein kinase, resulted in significantly reduced root hair and
root cell lengths. Inactivation of CDPK1 is also associated with significant
diminution of both rhizobial and mycorrhizal symbiotic colonization.
Additionally, microarray analysis revealed that silencing CDPK1 alters cell wall
and defense-related gene expression. We propose that M. truncatula CDPK1 is a key
component of one or more signaling pathways that directly or indirectly modulates
cell expansion or cell wall synthesis, possibly altering defense gene expression
and symbiotic interactions.
FAU - Ivashuta, Sergey
AU - Ivashuta S
AD - Department of Plant Biology, University of Minesota, St. Paul, Minesota 55108,
USA.
FAU - Liu, Jinyuan
AU - Liu J
FAU - Liu, Junqi
AU - Liu J
FAU - Lohar, Dasharath P
AU - Lohar DP
FAU - Haridas, Sajeet
AU - Haridas S
FAU - Bucciarelli, Bruna
AU - Bucciarelli B
FAU - VandenBosch, Kathryn A
AU - VandenBosch KA
FAU - Vance, Carroll P
AU - Vance CP
FAU - Harrison, Maria J
AU - Harrison MJ
FAU - Gantt, J Stephen
AU - Gantt JS
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
PT - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20050930
PL - England
TA - Plant Cell
JT - The Plant cell
JID - 9208688
RN - 0 (ATCDPK1 protein, Arabidopsis)
RN - 0 (Arabidopsis Proteins)
RN - 0 (Calcium-Binding Proteins)
RN - EC 2.7.- (Protein Kinases)
RN - SY7Q814VUP (Calcium)
SB - IM
MH - Arabidopsis Proteins/genetics/metabolism
MH - Calcium/metabolism
MH - Calcium Signaling/physiology
MH - Calcium-Binding Proteins/genetics/isolation & purification/*metabolism
MH - Cell Wall/enzymology/genetics
MH - Gene Expression Regulation, Enzymologic/physiology
MH - Gene Expression Regulation, Plant/genetics
MH - Gene Silencing/physiology
MH - Immunity, Innate/genetics
MH - Medicago truncatula/*enzymology/genetics/*growth & development
MH - Plant Diseases/genetics
MH - Plant Roots/*enzymology/genetics/*growth & development
MH - Protein Kinases/genetics/isolation & purification/*metabolism
MH - RNA Interference/physiology
MH - Signal Transduction/genetics
MH - Symbiosis/genetics
PMC - PMC1276019
EDAT- 2005/10/04 09:00
MHDA- 2006/05/27 09:00
CRDT- 2005/10/04 09:00
PHST- 2005/10/04 09:00 [pubmed]
PHST- 2006/05/27 09:00 [medline]
PHST- 2005/10/04 09:00 [entrez]
AID - tpc.105.035394 [pii]
AID - 035394 [pii]
AID - 10.1105/tpc.105.035394 [doi]
PST - ppublish
SO - Plant Cell. 2005 Nov;17(11):2911-21. doi: 10.1105/tpc.105.035394. Epub 2005 Sep
30.
##### PUB RECORD #####
## 10.1111/j.1469-8137.2011.03718.x 21679315 PMC3206218 Godiard, Lepage, et al., 2011 "Godiard L, Lepage A, Moreau S, Laporte D, Verdenaud M, Timmers T, Gamas P. MtbHLH1, a bHLH transcription factor involved in Medicago truncatula nodule vascular patterning and nodule to plant metabolic exchanges. New Phytol. 2011 Jul;191(2):391-404. doi: 10.1111/j.1469-8137.2011.03718.x. Epub 2011 Jun 17. PMID: 21679315; PMCID: PMC3206218." ##
PMID- 21679315
OWN - NLM
STAT- MEDLINE
DCOM- 20130328
LR - 20220310
IS - 1469-8137 (Electronic)
IS - 0028-646X (Print)
IS - 0028-646X (Linking)
VI - 191
IP - 2
DP - 2011 Jul
TI - MtbHLH1, a bHLH transcription factor involved in Medicago truncatula nodule
vascular patterning and nodule to plant metabolic exchanges.
PG - 391-404
LID - 10.1111/j.1469-8137.2011.03718.x [doi]
AB - This study aimed at defining the role of a basic helix-loop-helix (bHLH)
transcription factor gene from Medicago truncatula, MtbHLH1, whose expression is
upregulated during the development of root nodules produced upon infection by
rhizobia bacteria. We used MtbHLH1 promoter::GUS fusions and quantitative
reverse-transcription polymerase chain reaction analyses to finely characterize
the MtbHLH1 expression pattern. We altered MtbHLH1 function by expressing a
dominantly repressed construct (CRES-T approach) and looked for possible MtbHLH1
target genes by transcriptomics. We found that MtbHLH1 is expressed in nodule
primordia cells derived from pericycle divisions, in nodule vascular bundles
(VBs) and in uninfected cells of the nitrogen (N) fixation zone. MtbHLH1 is also
expressed in root tips, lateral root primordia cells and root VBs, and induced
upon auxin treatment. Altering MtbHLH1 function led to an unusual phenotype, with
a modified patterning of nodule VB development and a reduced growth of aerial
parts of the plant, even though the nodules were able to fix atmospheric N.
Several putative MtbHLH1 regulated genes were identified, including an asparagine
synthase and a LOB (lateral organ boundary) transcription factor. Our results
suggest that the MtbHLH1 gene is involved in the control of nodule vasculature
patterning and nutrient exchanges between nodules and roots.
CI - (c) 2011 The Authors. New Phytologist (c) 2011 New Phytologist Trust.
FAU - Godiard, Laurence
AU - Godiard L
AD - Laboratoire des Interactions Plantes Microorganismes, Unite Mixte de Recherche,
Institut National de la Recherche Agronomique - Centre National de la Recherche
Scientifique 441/2594, F-31320 Castanet Tolosan, France.
FAU - Lepage, Agnes
AU - Lepage A
AD - Laboratoire des Interactions Plantes Microorganismes, Unite Mixte de Recherche,
Institut National de la Recherche Agronomique - Centre National de la Recherche
Scientifique 441/2594, F-31320 Castanet Tolosan, France.
FAU - Moreau, Sandra
AU - Moreau S
AD - Laboratoire des Interactions Plantes Microorganismes, Unite Mixte de Recherche,
Institut National de la Recherche Agronomique - Centre National de la Recherche
Scientifique 441/2594, F-31320 Castanet Tolosan, France.
FAU - Laporte, Damien
AU - Laporte D
AD - Jian-Qiu Wu's laboratory, Ohio State University, 612 Biosciences Building, 484 W
12th Ave, Columbus, OH 43210, USA.
FAU - Verdenaud, Marion
AU - Verdenaud M
AD - Laboratoire des Interactions Plantes Microorganismes, Unite Mixte de Recherche,
Institut National de la Recherche Agronomique - Centre National de la Recherche
Scientifique 441/2594, F-31320 Castanet Tolosan, France.
FAU - Timmers, Ton
AU - Timmers T
AD - Laboratoire des Interactions Plantes Microorganismes, Unite Mixte de Recherche,
Institut National de la Recherche Agronomique - Centre National de la Recherche
Scientifique 441/2594, F-31320 Castanet Tolosan, France.
FAU - Gamas, Pascal
AU - Gamas P
AD - Laboratoire des Interactions Plantes Microorganismes, Unite Mixte de Recherche,
Institut National de la Recherche Agronomique - Centre National de la Recherche
Scientifique 441/2594, F-31320 Castanet Tolosan, France.
LA - eng
SI - GENBANK/FR697055
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20110617
PL - England
TA - New Phytol
JT - The New phytologist
JID - 9882884
RN - 0 (Basic Helix-Loop-Helix Transcription Factors)
RN - 0 (Indoleacetic Acids)
RN - 0 (Plant Growth Regulators)
RN - 0 (Plant Proteins)
SB - IM
MH - Basic Helix-Loop-Helix Transcription Factors/genetics/*metabolism
MH - Body Patterning
MH - Gene Expression Profiling
MH - Gene Expression Regulation, Plant/drug effects
MH - Indoleacetic Acids/pharmacology
MH - Medicago truncatula/genetics/*metabolism/microbiology/physiology
MH - Molecular Sequence Data
MH - Nitrogen Fixation/genetics
MH - Phenotype
MH - Plant Growth Regulators/pharmacology
MH - Plant Proteins/genetics/metabolism
MH - Plant Root Nodulation
MH - Plants, Genetically Modified
MH - Promoter Regions, Genetic
MH - Rhizobium/genetics/*physiology
MH - Root Nodules, Plant/genetics/growth & development/*metabolism
MH - Symbiosis/genetics
PMC - PMC3206218
EDAT- 2011/06/18 06:00
MHDA- 2013/03/30 06:00
CRDT- 2011/06/18 06:00
PHST- 2011/06/18 06:00 [entrez]
PHST- 2011/06/18 06:00 [pubmed]
PHST- 2013/03/30 06:00 [medline]
AID - 10.1111/j.1469-8137.2011.03718.x [doi]
PST - ppublish
SO - New Phytol. 2011 Jul;191(2):391-404. doi: 10.1111/j.1469-8137.2011.03718.x. Epub
2011 Jun 17.
##### PUB RECORD #####
## 10.1111/j.1365-313x.2009.04072.x 19912567 null Pumplin, Mondo, et al., 2009 "Pumplin N, Mondo SJ, Topp S, Starker CG, Gantt JS, Harrison MJ. Medicago truncatula Vapyrin is a novel protein required for arbuscular mycorrhizal symbiosis. Plant J. 2010 Feb 1;61(3):482-94. doi: 10.1111/j.1365-313X.2009.04072.x. Epub 2009 Nov 14. PMID: 19912567." ##
PMID- 19912567
OWN - NLM
STAT- MEDLINE
DCOM- 20100830
LR - 20100422
IS - 1365-313X (Electronic)
IS - 0960-7412 (Linking)
VI - 61
IP - 3
DP - 2010 Feb 1
TI - Medicago truncatula Vapyrin is a novel protein required for arbuscular
mycorrhizal symbiosis.
PG - 482-94
LID - 10.1111/j.1365-313X.2009.04072.x [doi]
AB - Arbuscular mycorrhizal (AM) symbiosis is a widespread mutualism formed between
vascular plants and fungi of the Glomeromycota. In this endosymbiosis, fungal
hyphae enter the roots, growing through epidermal cells to the cortex where they
establish differentiated hyphae called arbuscules in the cortical cells.
Reprogramming of the plant epidermal and cortical cells occurs to enable
intracellular growth of the fungal symbiont; however, the plant genes underlying
this process are largely unknown. Here, through the use of RNAi, we demonstrate
that the expression of a Medicago truncatula gene named Vapyrin is essential for
arbuscule formation, and also for efficient epidermal penetration by AM fungi.
Vapyrin is induced transiently in the epidermis coincident with hyphal
penetration, and then in the cortex during arbuscule formation. The Vapyrin
protein is cytoplasmic, and in cells containing AM fungal hyphae, the protein
accumulates in small puncta that move through the cytoplasm. Vapyrin is a novel
protein composed of two domains that mediate protein-protein interactions: an
N-terminal VAMP-associated protein (VAP)/major sperm protein (MSP) domain and a
C-terminal ankyrin-repeat domain. Putative Vapyrin orthologs exist widely in the
plant kingdom, but not in Arabidopsis, or in non-plant species. The data suggest
a role for Vapyrin in cellular remodeling to support the intracellular
development of fungal hyphae during AM symbiosis.
FAU - Pumplin, Nathan
AU - Pumplin N
AD - Boyce Thompson Institute for Plant Research, Tower Road, Ithaca, NY 14853, USA.
FAU - Mondo, Stephen J
AU - Mondo SJ
FAU - Topp, Stephanie
AU - Topp S
FAU - Starker, Colby G
AU - Starker CG
FAU - Gantt, J Stephen
AU - Gantt JS
FAU - Harrison, Maria J
AU - Harrison MJ
LA - eng
PT - Journal Article
PT - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20091114
PL - England
TA - Plant J
JT - The Plant journal : for cell and molecular biology
JID - 9207397
RN - 0 (Plant Proteins)
RN - 0 (Vesicular Transport Proteins)
SB - IM
MH - Amino Acid Sequence
MH - Animals
MH - Gene Expression Regulation, Plant
MH - Humans
MH - Medicago truncatula/chemistry/genetics/*metabolism
MH - Molecular Sequence Data
MH - Mycorrhizae/*metabolism
MH - Phylogeny
MH - Plant Proteins/chemistry/genetics/*metabolism
MH - RNA Interference
MH - *Symbiosis
MH - Vesicular Transport Proteins/chemistry/genetics/*metabolism
EDAT- 2009/11/17 06:00
MHDA- 2010/08/31 06:00
CRDT- 2009/11/17 06:00
PHST- 2009/11/17 06:00 [entrez]
PHST- 2009/11/17 06:00 [pubmed]
PHST- 2010/08/31 06:00 [medline]
AID - TPJ4072 [pii]
AID - 10.1111/j.1365-313X.2009.04072.x [doi]
PST - ppublish
SO - Plant J. 2010 Feb 1;61(3):482-94. doi: 10.1111/j.1365-313X.2009.04072.x. Epub
2009 Nov 14.
##### PUB RECORD #####
## 10.1105/tpc.15.00476 26410301 PMC4682322 Jun, Liu, et al., 2015 "Jun JH, Liu C, Xiao X, Dixon RA. The Transcriptional Repressor MYB2 Regulates Both Spatial and Temporal Patterns of Proanthocyandin and Anthocyanin Pigmentation in Medicago truncatula. Plant Cell. 2015 Oct;27(10):2860-79. doi: 10.1105/tpc.15.00476. Epub 2015 Sep 26. PMID: 26410301; PMCID: PMC4682322." ##
PMID- 26410301
OWN - NLM
STAT- MEDLINE
DCOM- 20170905
LR - 20220310
IS - 1532-298X (Electronic)
IS - 1040-4651 (Print)
IS - 1040-4651 (Linking)
VI - 27
IP - 10
DP - 2015 Oct
TI - The Transcriptional Repressor MYB2 Regulates Both Spatial and Temporal Patterns
of Proanthocyandin and Anthocyanin Pigmentation in Medicago truncatula.
PG - 2860-79
LID - 10.1105/tpc.15.00476 [doi]
AB - Accumulation of anthocyanins and proanthocyanidins (PAs) is limited to specific
cell types and developmental stages, but little is known about how
antagonistically acting transcriptional regulators work together to determine
temporal and spatial patterning of pigmentation at the cellular level, especially
for PAs. Here, we characterize MYB2, a transcriptional repressor regulating both
anthocyanin and PA biosynthesis in the model legume Medicago truncatula. MYB2 was
strongly upregulated by MYB5, a major regulator of PA biosynthesis in M.
truncatula and a component of MYB-basic helix loop helix-WD40 (MBW) activator
complexes. Overexpression of MYB2 abolished anthocyanin and PA accumulation in M.
truncatula hairy roots and Arabidopsis thaliana seeds, respectively. Anthocyanin
deposition was expanded in myb2 mutant seedlings and flowers accompanied by
increased anthocyanin content. PA mainly accumulated in the epidermal layer
derived from the outer integument in the M. truncatula seed coat, starting from
the hilum area. The area of PA accumulation and ANTHOCYANIDIN REDUCTASE
expression was expanded into the seed body at the early stage of seed development
in the myb2 mutant. Genetic, biochemical, and cell biological evidence suggests
that MYB2 functions as part of a multidimensional regulatory network to define
the temporal and spatial pattern of anthocyanin and PA accumulation linked to
developmental processes.
CI - (c) 2015 American Society of Plant Biologists. All rights reserved.
FAU - Jun, Ji Hyung
AU - Jun JH
AUID- ORCID: 0000-0002-2563-4144
AD - Department of Biological Sciences, University of North Texas, Denton, Texas
76203-5017.
FAU - Liu, Chenggang
AU - Liu C
AUID- ORCID: 0000-0002-0576-8567
AD - Department of Biological Sciences, University of North Texas, Denton, Texas
76203-5017.
FAU - Xiao, Xirong
AU - Xiao X
AUID- ORCID: 0000-0002-1785-6417
AD - Department of Biological Sciences, University of North Texas, Denton, Texas
76203-5017.
FAU - Dixon, Richard A
AU - Dixon RA
AUID- ORCID: 0000-0001-8393-9408
AD - Department of Biological Sciences, University of North Texas, Denton, Texas
76203-5017 richard.dixon@unt.edu.
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20150926
PL - England
TA - Plant Cell
JT - The Plant cell
JID - 9208688
RN - 0 (Anthocyanins)
RN - 0 (Plant Proteins)
RN - 0 (Proanthocyanidins)
RN - 0 (Transcription Factors)
RN - EC 1.- (Oxidoreductases)
SB - IM
MH - Anthocyanins/*metabolism
MH - Arabidopsis/cytology/genetics/metabolism
MH - Flowers/cytology/genetics/metabolism
MH - Gene Expression
MH - *Gene Expression Regulation, Plant
MH - Medicago truncatula/cytology/*genetics/metabolism
MH - Mutation
MH - Oxidoreductases/genetics/metabolism
MH - Phylogeny
MH - Pigmentation
MH - Plant Proteins/genetics/metabolism
MH - Plant Roots/cytology/genetics/metabolism
MH - Plants, Genetically Modified
MH - Proanthocyanidins/*metabolism
MH - Seedlings/cytology/genetics/metabolism
MH - Seeds/cytology/genetics/metabolism
MH - Transcription Factors/genetics/*metabolism
PMC - PMC4682322
EDAT- 2015/09/28 06:00
MHDA- 2017/09/07 06:00
CRDT- 2015/09/28 06:00
PHST- 2015/05/29 00:00 [received]
PHST- 2015/09/10 00:00 [accepted]
PHST- 2015/09/28 06:00 [entrez]
PHST- 2015/09/28 06:00 [pubmed]
PHST- 2017/09/07 06:00 [medline]
AID - tpc.15.00476 [pii]
AID - TPC201500476RAR2 [pii]
AID - 10.1105/tpc.15.00476 [doi]
PST - ppublish
SO - Plant Cell. 2015 Oct;27(10):2860-79. doi: 10.1105/tpc.15.00476. Epub 2015 Sep 26.
##### PUB RECORD #####
## 10.1104/pp.111.180182 21685176 PMC3149922 Laurie, Diwadkar, et al., 2011 "Laurie RE, Diwadkar P, Jaudal M, Zhang L, Hecht V, Wen J, Tadege M, Mysore KS, Putterill J, Weller JL, Macknight RC. The Medicago FLOWERING LOCUS T homolog, MtFTa1, is a key regulator of flowering time. Plant Physiol. 2011 Aug;156(4):2207-24. doi: 10.1104/pp.111.180182. Epub 2011 Jun 17. PMID: 21685176; PMCID: PMC3149922." ##
PMID- 21685176
OWN - NLM
STAT- MEDLINE
DCOM- 20111205
LR - 20211020
IS - 1532-2548 (Electronic)
IS - 0032-0889 (Print)
IS - 0032-0889 (Linking)
VI - 156
IP - 4
DP - 2011 Aug
TI - The Medicago FLOWERING LOCUS T homolog, MtFTa1, is a key regulator of flowering
time.
PG - 2207-24
LID - 10.1104/pp.111.180182 [doi]
AB - FLOWERING LOCUS T (FT) genes encode proteins that function as the mobile floral
signal, florigen. In this study, we characterized five FT-like genes from the
model legume, Medicago (Medicago truncatula). The different FT genes showed
distinct patterns of expression and responses to environmental cues. Three of the
FT genes (MtFTa1, MtFTb1, and MtFTc) were able to complement the Arabidopsis
(Arabidopsis thaliana) ft-1 mutant, suggesting that they are capable of
functioning as florigen. MtFTa1 is the only one of the FT genes that is
up-regulated by both long days (LDs) and vernalization, conditions that promote
Medicago flowering, and transgenic Medicago plants overexpressing the MtFTa1 gene
flowered very rapidly. The key role MtFTa1 plays in regulating flowering was
demonstrated by the identification of fta1 mutants that flowered significantly
later in all conditions examined. fta1 mutants do not respond to vernalization
but are still responsive to LDs, indicating that the induction of flowering by
prolonged cold acts solely through MtFTa1, whereas photoperiodic induction of
flowering involves other genes, possibly MtFTb1, which is only expressed in
leaves under LD conditions and therefore might contribute to the photoperiodic
regulation of flowering. The role of the MtFTc gene is unclear, as the ftc
mutants did not have any obvious flowering-time or other phenotypes. Overall,
this work reveals the diversity of the regulation and function of the Medicago FT
family.
FAU - Laurie, Rebecca E
AU - Laurie RE
AD - Department of Biochemistry, University of Otago, Dunedin 9054, New Zealand.
FAU - Diwadkar, Payal
AU - Diwadkar P
FAU - Jaudal, Mauren
AU - Jaudal M
FAU - Zhang, Lulu
AU - Zhang L
FAU - Hecht, Valerie
AU - Hecht V
FAU - Wen, Jiangqi
AU - Wen J
FAU - Tadege, Million
AU - Tadege M
FAU - Mysore, Kirankumar S
AU - Mysore KS
FAU - Putterill, Joanna
AU - Putterill J
FAU - Weller, James L
AU - Weller JL
FAU - Macknight, Richard C
AU - Macknight RC
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20110617
PL - United States
TA - Plant Physiol
JT - Plant physiology
JID - 0401224
RN - 0 (Plant Proteins)
SB - IM
MH - Amino Acid Sequence
MH - Arabidopsis/genetics
MH - Cold Temperature
MH - Flowers/genetics/growth & development/*physiology
MH - Gene Expression Regulation, Plant
MH - Genes, Plant/genetics
MH - Genetic Complementation Test
MH - Medicago/genetics/growth & development/*physiology
MH - Meristem/genetics
MH - Molecular Sequence Data
MH - Mutation/genetics
MH - Phenotype
MH - Photoperiod
MH - Plant Proteins/chemistry/genetics/*metabolism
MH - Plants, Genetically Modified
MH - *Sequence Homology, Amino Acid
MH - Time Factors
MH - Up-Regulation/genetics
PMC - PMC3149922
EDAT- 2011/06/21 06:00
MHDA- 2011/12/13 00:00
CRDT- 2011/06/21 06:00
PHST- 2011/06/21 06:00 [entrez]
PHST- 2011/06/21 06:00 [pubmed]
PHST- 2011/12/13 00:00 [medline]
AID - pp.111.180182 [pii]
AID - 180182 [pii]
AID - 10.1104/pp.111.180182 [doi]
PST - ppublish
SO - Plant Physiol. 2011 Aug;156(4):2207-24. doi: 10.1104/pp.111.180182. Epub 2011 Jun
17.
##### PUB RECORD #####
## 10.1094/mpmi-06-10-0144 20731530 null Miyahara, Richens, et al., 2010 "Miyahara A, Richens J, Starker C, Morieri G, Smith L, Long S, Downie JA, Oldroyd GE. Conservation in function of a SCAR/WAVE component during infection thread and root hair growth in Medicago truncatula. Mol Plant Microbe Interact. 2010 Dec;23(12):1553-62. doi: 10.1094/MPMI-06-10-0144. PMID: 20731530." ##
PMID- 20731530
OWN - NLM
STAT- MEDLINE
DCOM- 20110111
LR - 20220310
IS - 0894-0282 (Print)
IS - 0894-0282 (Linking)
VI - 23
IP - 12
DP - 2010 Dec
TI - Conservation in function of a SCAR/WAVE component during infection thread and
root hair growth in Medicago truncatula.
PG - 1553-62
LID - 10.1094/MPMI-06-10-0144 [doi]
AB - Nitrogen-fixing symbioses of plants are often associated with bacterially
infected nodules where nitrogen fixation occurs. The plant host facilitates
bacterial infection with the formation of infection threads, unique structures
associated with these symbioses, which are invaginations of the host cell with
the capability of traversing cellular junctions. Here, we show that the infection
thread shares mechanistic similarities to polar-growing cells, because the
required for infection thread (RIT) locus of Medicago truncatula has roles in
root-hair, trichome, and infection-thread growth. We show that RIT encodes the M.
truncatula ortholog of NAP1, a component of the SCAR/WAVE (suppressor of cAMP
receptor/WASP-family verprolin homologous protein) complex that regulates actin
polymerization, through the activation of ARP2/3. NAP1 of Arabidopsis thaliana
functions equivalently to the M. truncatula gene, indicating that the mode of
action of NAP1 is functionally conserved across species and that legumes have not
evolved a unique functionality for NAP1 during rhizobial colonization. This work
highlights the surprising commonality between polar-growing cells and a
polar-growing cellular intrusion and reveals important insights into the
formation and maintenance of infection-thread development.
FAU - Miyahara, Akira
AU - Miyahara A
AD - Department of Disease and Stress Biology, John Innes Centre, Norwich Research
Park, Colney Lane, Norwich, NR4 7UH, UK.
FAU - Richens, Jennifer
AU - Richens J
FAU - Starker, Colby
AU - Starker C
FAU - Morieri, Giulia
AU - Morieri G
FAU - Smith, Lucinda
AU - Smith L
FAU - Long, Sharon
AU - Long S
FAU - Downie, J Allan
AU - Downie JA
FAU - Oldroyd, Giles E D
AU - Oldroyd GE
LA - eng
SI - GENBANK/HM590708
GR - BBS/E/J/000CA336/BB_/Biotechnology and Biological Sciences Research
Council/United Kingdom
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
PL - United States
TA - Mol Plant Microbe Interact
JT - Molecular plant-microbe interactions : MPMI
JID - 9107902
RN - 0 (Plant Proteins)
SB - IM
MH - Gene Expression Regulation, Plant/*physiology
MH - Medicago truncatula/genetics/*metabolism
MH - Molecular Sequence Data
MH - Mutation
MH - Plant Proteins/genetics/*metabolism
MH - Plant Root Nodulation/*physiology
MH - Plant Roots/*growth & development/physiology
MH - Symbiosis
EDAT- 2010/08/25 06:00
MHDA- 2011/01/12 06:00
CRDT- 2010/08/25 06:00
PHST- 2010/08/25 06:00 [entrez]
PHST- 2010/08/25 06:00 [pubmed]
PHST- 2011/01/12 06:00 [medline]
AID - 10.1094/MPMI-06-10-0144 [doi]
PST - ppublish
SO - Mol Plant Microbe Interact. 2010 Dec;23(12):1553-62. doi:
10.1094/MPMI-06-10-0144.
##### PUB RECORD #####
## 10.1111/j.1365-313x.2006.02910.x 17132148 null Gargantini, Gonzalez-Rizzo, et al., 2006 "Gargantini PR, Gonzalez-Rizzo S, Chinchilla D, Raices M, Giammaria V, Ulloa RM, Frugier F, Crespi MD. A CDPK isoform participates in the regulation of nodule number in Medicago truncatula. Plant J. 2006 Dec;48(6):843-56. doi: 10.1111/j.1365-313X.2006.02910.x. Epub 2006 Nov 21. PMID: 17132148." ##
PMID- 17132148
OWN - NLM
STAT- MEDLINE
DCOM- 20070417
LR - 20220408
IS - 0960-7412 (Print)
IS - 0960-7412 (Linking)
VI - 48
IP - 6
DP - 2006 Dec
TI - A CDPK isoform participates in the regulation of nodule number in Medicago
truncatula.
PG - 843-56
AB - Medicago spp. are able to develop root nodules via symbiotic interaction with
Sinorhizobium meliloti. Calcium-dependent protein kinases (CDPKs) are involved in
various signalling pathways in plants, and we found that expression of MtCPK3, a
CDPK isoform present in roots of the model legume Medicago truncatula, is
regulated during the nodulation process. Early inductions were detected 15 min
and 3-4 days post-inoculation (dpi). The very early induction of CPK3 messengers
was also present in inoculated M. truncatula dmi mutants and in wild-type roots
subjected to salt stress, indicating that this rapid response is probably
stress-related. In contrast, the later response was concomitant with cortical
cell division and the formation of nodule primordia, and was not observed in
wild-type roots inoculated with nod (-) strains. This late induction correlated
with a change in the subcellular distribution of CDPK activities. Accordingly, an
anti-MtCPK3 antibody detected two bands in soluble root extracts and one in the
particulate fraction. CPK3::GFP fusions are targeted to the plasma membrane in
epidermal onion cells, a localization that depends on myristoylation and
palmitoylation sites of the protein, suggesting a dual subcellular localization.
MtCPK3 mRNA and protein were also up-regulated by cytokinin treatment, a hormone
linked to the regulation of cortical cell division and other nodulation-related
responses. An RNAi-CDPK construction was used to silence CPK3 in Agrobacterium
rhizogenes-transformed roots. Although no major phenotype was detected in these
roots, when infected with rhizobia, the total number of nodules was, on average,
twofold higher than in controls. This correlates with the lack of MtCPK3
induction in the inoculated super-nodulator sunn mutant. Our results suggest that
CPK3 participates in the regulation of the symbiotic interaction.
FAU - Gargantini, Pablo R
AU - Gargantini PR
AD - Instituto de Investigaciones en Ingenieria Genetica y Biologia Molecular, Vuelta
de Obligado 2490, 2 piso, 1428 Buenos Aires, Argentina.
FAU - Gonzalez-Rizzo, Silvina
AU - Gonzalez-Rizzo S
FAU - Chinchilla, Delphine
AU - Chinchilla D
FAU - Raices, Marcela
AU - Raices M
FAU - Giammaria, Veronica
AU - Giammaria V
FAU - Ulloa, Rita M
AU - Ulloa RM
FAU - Frugier, Florian
AU - Frugier F
FAU - Crespi, Martin D
AU - Crespi MD
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20061121
PL - England
TA - Plant J
JT - The Plant journal : for cell and molecular biology
JID - 9207397
RN - 0 (Cytokinins)
RN - 0 (Isoenzymes)
RN - 0 (Plant Proteins)
RN - 0 (RNA, Messenger)
RN - 0 (RNA, Plant)
RN - 147336-22-9 (Green Fluorescent Proteins)
RN - EC 2.7.11.17 (Calcium-Calmodulin-Dependent Protein Kinases)
SB - IM
MH - Calcium-Calmodulin-Dependent Protein Kinases/genetics/*metabolism
MH - Cytokinins/pharmacology
MH - Gene Expression Regulation, Enzymologic
MH - Gene Expression Regulation, Plant
MH - Genes, Plant
MH - Green Fluorescent Proteins/genetics
MH - Isoenzymes/genetics/metabolism
MH - Medicago sativa/enzymology
MH - Medicago truncatula/*enzymology/genetics/microbiology
MH - Onions/cytology
MH - Plant Proteins/genetics/*metabolism
MH - Plant Roots/*enzymology/microbiology
MH - RNA Interference
MH - RNA, Messenger
MH - RNA, Plant
MH - Rhizobium/enzymology
MH - Sinorhizobium meliloti/physiology
MH - Symbiosis/*physiology
MH - Up-Regulation
EDAT- 2006/11/30 09:00
MHDA- 2007/04/18 09:00
CRDT- 2006/11/30 09:00
PHST- 2006/11/30 09:00 [pubmed]
PHST- 2007/04/18 09:00 [medline]
PHST- 2006/11/30 09:00 [entrez]
AID - TPJ2910 [pii]
AID - 10.1111/j.1365-313X.2006.02910.x [doi]
PST - ppublish
SO - Plant J. 2006 Dec;48(6):843-56. doi: 10.1111/j.1365-313X.2006.02910.x. Epub 2006
Nov 21.
##### PUB RECORD #####
## 10.1105/tpc.019406 15037734 PMC412876 Campalans, Kondorosi, et al., 2017 "Campalans A, Kondorosi A, Crespi M. Enod40, a short open reading frame-containing mRNA, induces cytoplasmic localization of a nuclear RNA binding protein in Medicago truncatula. Plant Cell. 2004 Apr;16(4):1047-59. doi: 10.1105/tpc.019406. Epub 2004 Mar 22. Erratum in: Plant Cell. 2017 Apr;29(4):912. PMID: 15037734; PMCID: PMC412876." ##
PMID- 15037734
OWN - NLM
STAT- MEDLINE
DCOM- 20040625
LR - 20181113
IS - 1040-4651 (Print)
IS - 1532-298X (Electronic)
IS - 1040-4651 (Linking)
VI - 16
IP - 4
DP - 2004 Apr
TI - Enod40, a short open reading frame-containing mRNA, induces cytoplasmic
localization of a nuclear RNA binding protein in Medicago truncatula.
PG - 1047-59
AB - In eukaryotes, diverse mRNAs containing only short open reading frames
(sORF-mRNAs) are induced at specific stages of development. Their mechanisms of
action may involve the RNA itself and/or sORF-encoded oligopeptides. Enod40 genes
code for highly structured plant sORF-mRNAs involved in root nodule
organogenesis. A novel RNA binding protein interacting with the enod40 RNA,
MtRBP1 (for Medicago truncatula RNA Binding Protein 1), was identified using a
yeast three-hybrid screening. Immunolocalization studies and use of a
MtRBP1-DsRed2 fluorescent protein fusion showed that MtRBP1 localized to nuclear
speckles in plant cells but was exported into the cytoplasm during nodule
development in enod40-expressing cells. Direct involvement of the enod40 RNA in
MtRBP1 relocalization into cytoplasmic granules was shown using a transient
expression assay. Using a (green fluorescent protein)/MS2 bacteriophage system to
tag the enod40 RNA, we detected in vivo colocalization of the enod40 RNA and
MtRBP1 in these granules. This in vivo approach to monitor RNA-protein
interactions allowed us to demonstrate that cytoplasmic relocalization of nuclear
proteins is an RNA-mediated cellular function of a sORF-mRNA.
FAU - Campalans, Anna
AU - Campalans A
AD - Institut des Sciences du Vegetal, Centre National de la Recherche Scientifique,
91198 Gif sur Yvette, France.
FAU - Kondorosi, Adam
AU - Kondorosi A
FAU - Crespi, Martin
AU - Crespi M
LA - eng
SI - GENBANK/AJ508392
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20040322
PL - England
TA - Plant Cell
JT - The Plant cell
JID - 9208688
RN - 0 (DNA, Plant)
RN - 0 (DNA-Binding Proteins)
RN - 0 (ENOD40 RNA)
RN - 0 (Nuclear Proteins)
RN - 0 (Plant Proteins)
RN - 0 (RNA, Long Noncoding)
RN - 0 (RNA, Messenger)
RN - 0 (RNA, Plant)
RN - 0 (RNA, Untranslated)
RN - 0 (Recombinant Fusion Proteins)
SB - IM
EIN - Plant Cell. 2017 Apr;29(4):912. PMID: 28351988
MH - Amino Acid Sequence
MH - Base Sequence
MH - Cytoplasm/metabolism
MH - DNA, Plant/genetics
MH - DNA-Binding Proteins/genetics/metabolism
MH - Gene Expression
MH - Medicago/*genetics/*metabolism
MH - Molecular Sequence Data
MH - Nuclear Proteins/genetics/metabolism
MH - Onions/genetics/metabolism
MH - Plant Proteins/genetics/metabolism
MH - Plants, Genetically Modified
MH - RNA, Long Noncoding
MH - RNA, Messenger/*genetics
MH - RNA, Plant/*genetics
MH - RNA, Untranslated/*genetics
MH - Recombinant Fusion Proteins/genetics/metabolism
MH - Sequence Homology, Amino Acid
MH - Two-Hybrid System Techniques
PMC - PMC412876
EDAT- 2004/03/24 05:00
MHDA- 2004/06/26 05:00
CRDT- 2004/03/24 05:00
PHST- 2004/03/24 05:00 [pubmed]
PHST- 2004/06/26 05:00 [medline]
PHST- 2004/03/24 05:00 [entrez]
AID - tpc.019406 [pii]
AID - 019406 [pii]
AID - 10.1105/tpc.019406 [doi]
PST - ppublish
SO - Plant Cell. 2004 Apr;16(4):1047-59. doi: 10.1105/tpc.019406. Epub 2004 Mar 22.
##### PUB RECORD #####
## 10.1073/pnas.0400595101 15070781 PMC384810 Mitra, Gleason, et al., 2004 "Mitra RM, Gleason CA, Edwards A, Hadfield J, Downie JA, Oldroyd GE, Long SR. A Ca2+/calmodulin-dependent protein kinase required for symbiotic nodule development: Gene identification by transcript-based cloning. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4701-5. doi: 10.1073/pnas.0400595101. Epub 2004 Mar 1. PMID: 15070781; PMCID: PMC384810." ##
PMID- 15070781
OWN - NLM
STAT- MEDLINE
DCOM- 20040719
LR - 20181113
IS - 0027-8424 (Print)
IS - 1091-6490 (Electronic)
IS - 0027-8424 (Linking)
VI - 101
IP - 13
DP - 2004 Mar 30
TI - A Ca2+/calmodulin-dependent protein kinase required for symbiotic nodule
development: Gene identification by transcript-based cloning.
PG - 4701-5
AB - In the establishment of the legume-rhizobial symbiosis, bacterial
lipochitooligosaccharide signaling molecules termed Nod factors activate the
formation of a novel root organ, the nodule. Nod factors elicit several responses
in plant root hair cells, including oscillations in cytoplasmic calcium levels
(termed calcium spiking) and alterations in root hair growth. A number of plant
mutants with defects in the Nod factor signaling pathway have been identified.
One such Medicago truncatula mutant, dmi3, exhibits calcium spiking and root hair
swelling in response to Nod factor, but fails to initiate symbiotic gene
expression or cell divisions for nodule formation. On the basis of these data, it
is thought that the dmi3 mutant perceives Nod factor but fails to transduce the
signal downstream of calcium spiking. Additionally, the dmi3 mutant is defective
in the symbiosis with mycorrhizal fungi, indicating the importance of the encoded
protein in multiple symbioses. We report the identification of the DMI3 gene,
using a gene cloning method based on transcript abundance. We show that
transcript-based cloning is a valid approach for cloning genes in barley,
indicating the value of this technology in crop plants. DMI3 encodes a
calcium/calmodulin-dependent protein kinase. Mutants in pea sym9 have phenotypes
similar to dmi3 and have alterations in this gene. The DMI3 class of proteins is
well conserved among plants that interact with mycorrhizal fungi, but it is less
conserved in Arabidopsis thaliana, which does not participate in the mycorrhizal
symbiosis.
FAU - Mitra, Raka M
AU - Mitra RM
AD - Department of Biological Sciences, 371 Serra Mall, Stanford University, Stanford,
CA 94305-5020, USA.
FAU - Gleason, Cynthia A
AU - Gleason CA
FAU - Edwards, Anne
AU - Edwards A
FAU - Hadfield, James
AU - Hadfield J
FAU - Downie, J Allan
AU - Downie JA
FAU - Oldroyd, Giles E D
AU - Oldroyd GE
FAU - Long, Sharon R
AU - Long SR
LA - eng
SI - GENBANK/AJ621916
SI - GENBANK/AY496049
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
PT - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20040301
PL - United States
TA - Proc Natl Acad Sci U S A
JT - Proceedings of the National Academy of Sciences of the United States of America
JID - 7505876
RN - 0 (DNA Primers)
RN - 0 (Recombinant Proteins)
RN - EC 2.7.11.17 (Calcium-Calmodulin-Dependent Protein Kinases)
SB - IM
CIN - Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4339-40. PMID: 15070718
MH - Amino Acid Sequence
MH - Base Sequence
MH - Calcium-Calmodulin-Dependent Protein Kinases/*genetics/*metabolism
MH - Cloning, Molecular
MH - Conserved Sequence
MH - DNA Primers
MH - Hordeum/enzymology/physiology
MH - Medicago/*enzymology/*physiology
MH - Molecular Sequence Data
MH - Mycorrhizae/physiology
MH - Recombinant Proteins/metabolism
MH - Reverse Transcriptase Polymerase Chain Reaction
MH - Sequence Alignment
MH - Sequence Homology, Amino Acid
MH - Symbiosis
MH - Transcription, Genetic
PMC - PMC384810
EDAT- 2004/04/09 05:00
MHDA- 2004/07/20 05:00
CRDT- 2004/04/09 05:00
PHST- 2004/04/09 05:00 [pubmed]
PHST- 2004/07/20 05:00 [medline]
PHST- 2004/04/09 05:00 [entrez]
AID - 0400595101 [pii]
AID - 1014701 [pii]
AID - 10.1073/pnas.0400595101 [doi]
PST - ppublish
SO - Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4701-5. doi:
10.1073/pnas.0400595101. Epub 2004 Mar 1.
##### PUB RECORD #####
## 10.1104/pp.105.069054 16244141 PMC1283775 Isayenkov, Mrosk, et al., 2005 "Isayenkov S, Mrosk C, Stenzel I, Strack D, Hause B. Suppression of allene oxide cyclase in hairy roots of Medicago truncatula reduces jasmonate levels and the degree of mycorrhization with Glomus intraradices. Plant Physiol. 2005 Nov;139(3):1401-10. doi: 10.1104/pp.105.069054. Epub 2005 Oct 21. PMID: 16244141; PMCID: PMC1283775." ##
PMID- 16244141
OWN - NLM
STAT- MEDLINE
DCOM- 20060209
LR - 20181113
IS - 0032-0889 (Print)
IS - 1532-2548 (Electronic)
IS - 0032-0889 (Linking)
VI - 139
IP - 3
DP - 2005 Nov
TI - Suppression of allene oxide cyclase in hairy roots of Medicago truncatula reduces
jasmonate levels and the degree of mycorrhization with Glomus intraradices.
PG - 1401-10
AB - During the symbiotic interaction between Medicago truncatula and the arbuscular
mycorrhizal (AM) fungus Glomus intraradices, an endogenous increase in jasmonic
acid (JA) occurs. Two full-length cDNAs coding for the JA-biosynthetic enzyme
allene oxide cyclase (AOC) from M. truncatula, designated as MtAOC1 and MtAOC2,
were cloned and characterized. The AOC protein was localized in plastids and
found to occur constitutively in all vascular tissues of M. truncatula. In leaves
and roots, MtAOCs are expressed upon JA application. Enhanced expression was also
observed during mycorrhization with G. intraradices. A partial suppression of
MtAOC expression was achieved in roots following transformation with
Agrobacterium rhizogenes harboring the MtAOC1 cDNA in the antisense direction
under control of the cauliflower mosaic virus 35S promoter. In comparison to
samples transformed with 35SuidA, roots with suppressed MtAOC1 expression
exhibited lower JA levels and a remarkable delay in the process of colonization
with G. intraradices. Both the mycorrhization rate, quantified by fungal rRNA,
and the arbuscule formation, analyzed by the expression level of the AM-specific
gene MtPT4, were affected. Staining of fungal material in roots with suppressed
MtAOC1 revealed a decreased number of arbuscules, but these did not exhibit an
altered structure. Our results indicate a crucial role for JA in the
establishment of AM symbiosis.
FAU - Isayenkov, Stanislav
AU - Isayenkov S
AD - Department of Secondary Metabolism , Leibniz Institute of Plant Biochemistry,
D-06120 Halle , Germany.
FAU - Mrosk, Cornelia
AU - Mrosk C
FAU - Stenzel, Irene
AU - Stenzel I
FAU - Strack, Dieter
AU - Strack D
FAU - Hause, Bettina
AU - Hause B
LA - eng
SI - GENBANK/AJ308489
SI - GENBANK/AJ866733
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20051021
PL - United States
TA - Plant Physiol
JT - Plant physiology
JID - 0401224
RN - 0 (Cyclopentanes)
RN - 0 (DNA, Complementary)
RN - 0 (Oxylipins)
RN - 0 (RNA, Messenger)
RN - 6RI5N05OWW (jasmonic acid)
RN - EC 5.3.- (Intramolecular Oxidoreductases)
RN - EC 5.3.99.6 (hydroperoxide isomerase)
SB - IM
MH - Cyclopentanes/*metabolism/pharmacology
MH - DNA, Complementary/genetics
MH - Gene Expression Profiling
MH - Gene Expression Regulation, Developmental
MH - Intramolecular Oxidoreductases/*antagonists & inhibitors/genetics/metabolism
MH - Medicago truncatula/*enzymology/microbiology
MH - Molecular Sequence Data
MH - Mycorrhizae/cytology/drug effects/*metabolism
MH - Organ Specificity
MH - Oxylipins
MH - Plant Leaves/cytology/drug effects
MH - Plant Roots/cytology/drug effects/*enzymology
MH - Plants, Genetically Modified
MH - Protein Transport
MH - RNA, Messenger/genetics/metabolism
MH - Symbiosis
MH - Transformation, Genetic
PMC - PMC1283775
EDAT- 2005/10/26 09:00
MHDA- 2006/02/10 09:00
CRDT- 2005/10/26 09:00
PHST- 2005/10/26 09:00 [pubmed]
PHST- 2006/02/10 09:00 [medline]
PHST- 2005/10/26 09:00 [entrez]
AID - pp.105.069054 [pii]
AID - 069054 [pii]
AID - 10.1104/pp.105.069054 [doi]
PST - ppublish
SO - Plant Physiol. 2005 Nov;139(3):1401-10. doi: 10.1104/pp.105.069054. Epub 2005 Oct
21.
##### PUB RECORD #####
## 10.1093/jxb/erw474 28073951 PMC6055581 Herrbach, Chirinos, et al., 2017 "Herrbach V, Chirinos X, Rengel D, Agbevenou K, Vincent R, Pateyron S, Huguet S, Balzergue S, Pasha A, Provart N, Gough C, Bensmihen S. Nod factors potentiate auxin signaling for transcriptional regulation and lateral root formation in Medicago truncatula. J Exp Bot. 2017 Jan 1;68(3):569-583. doi: 10.1093/jxb/erw474. PMID: 28073951; PMCID: PMC6055581." ##
PMID- 28073951
OWN - NLM
STAT- MEDLINE
DCOM- 20171117
LR - 20210109
IS - 1460-2431 (Electronic)
IS - 0022-0957 (Print)
IS - 0022-0957 (Linking)
VI - 68
IP - 3
DP - 2017 Jan 1
TI - Nod factors potentiate auxin signaling for transcriptional regulation and lateral
root formation in Medicago truncatula.
PG - 569-583
LID - 10.1093/jxb/erw474 [doi]
AB - Nodulation (Nod) factors (NFs) are symbiotic molecules produced by rhizobia that
are essential for establishment of the rhizobium-legume endosymbiosis. Purified
NFs can stimulate lateral root formation (LRF) in Medicago truncatula, but little
is known about the molecular mechanisms involved. Using a combination of reporter
constructs, pharmacological and genetic approaches, we show that NFs act on early
steps of LRF in M. truncatula, independently of the ethylene signaling pathway
and of the cytokinin receptor MtCRE1, but in interaction with auxin. We conducted
a whole-genome transcriptomic study upon NF and/or auxin treatments, using a
lateral root inducible system adapted for M. truncatula. This revealed a large
overlap between NF and auxin signaling and, more interestingly, synergistic
interactions between these molecules. Three groups showing interaction effects
were defined: group 1 contained more than 1500 genes responding specifically to
the combinatorial treatment of NFs and auxin; group 2 comprised auxin-regulated
genes whose expression was enhanced or antagonized by NFs; and in group 3 the
expression of NF regulated genes was antagonized by auxin. Groups 1 and 2 were
enriched in signaling and metabolic functions, which highlights important
crosstalk between NF and auxin signaling for both developmental and symbiotic
processes.
CI - (c) The Author 2017. Published by Oxford University Press on behalf of the Society
for Experimental Biology.
FAU - Herrbach, Violaine
AU - Herrbach V
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Chirinos, Ximena
AU - Chirinos X
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Rengel, David
AU - Rengel D
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Agbevenou, Kokoevi
AU - Agbevenou K
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Vincent, Remy
AU - Vincent R
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Pateyron, Stephanie
AU - Pateyron S
AD - POPS (transcriptOmic Platform of IPS2) Platform, Institute of Plant Sciences
Paris Saclay (IPS2), CNRS, INRA, Universite Paris-Sud, Universite Evry,
Universite Paris-Saclay, Orsay, France.
AD - Institute of Plant Sciences Paris-Saclay IPS2, Paris Diderot, Sorbonne
Paris-Cite, Orsay, France.
FAU - Huguet, Stephanie
AU - Huguet S
AD - POPS (transcriptOmic Platform of IPS2) Platform, Institute of Plant Sciences
Paris Saclay (IPS2), CNRS, INRA, Universite Paris-Sud, Universite Evry,
Universite Paris-Saclay, Orsay, France.
AD - Institute of Plant Sciences Paris-Saclay IPS2, Paris Diderot, Sorbonne
Paris-Cite, Orsay, France.
FAU - Balzergue, Sandrine
AU - Balzergue S
AD - POPS (transcriptOmic Platform of IPS2) Platform, Institute of Plant Sciences
Paris Saclay (IPS2), CNRS, INRA, Universite Paris-Sud, Universite Evry,
Universite Paris-Saclay, Orsay, France.
AD - Institute of Plant Sciences Paris-Saclay IPS2, Paris Diderot, Sorbonne
Paris-Cite, Orsay, France.
FAU - Pasha, Asher
AU - Pasha A
AD - Department of Cell & Systems Biology/ Centre for the Analysis of Genome Evolution
and Function, University of Toronto, Toronto, Canada.
FAU - Provart, Nicholas
AU - Provart N
AD - Department of Cell & Systems Biology/ Centre for the Analysis of Genome Evolution
and Function, University of Toronto, Toronto, Canada.
FAU - Gough, Clare
AU - Gough C
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Bensmihen, Sandra
AU - Bensmihen S
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
LA - eng
PT - Journal Article
PL - England
TA - J Exp Bot
JT - Journal of experimental botany
JID - 9882906
RN - 0 (Indoleacetic Acids)
RN - 0 (Lipopolysaccharides)
RN - 0 (Plant Growth Regulators)
SB - IM
MH - *Gene Expression Regulation, Plant
MH - Indoleacetic Acids/*metabolism
MH - Lipopolysaccharides/*physiology
MH - Medicago truncatula/genetics/growth & development/microbiology/*physiology
MH - Plant Growth Regulators/*metabolism
MH - Plant Roots/genetics/growth & development/microbiology
MH - Sinorhizobium meliloti/*physiology
PMC - PMC6055581
OTO - NOTNLM
OT - Auxin
OT - NimbleGen arrays
OT - Nod factors
OT - ethylene
OT - lateral root
OT - lateral root inducible system (LRIS)
OT - lipo-chitooligosaccharides (LCOs)
OT - symbiosis
OT - transcriptome
EDAT- 2017/01/12 06:00
MHDA- 2017/11/29 06:00
CRDT- 2017/01/12 06:00
PHST- 2017/01/12 06:00 [pubmed]
PHST- 2017/11/29 06:00 [medline]
PHST- 2017/01/12 06:00 [entrez]
AID - erw474 [pii]
AID - 10.1093/jxb/erw474 [doi]
PST - ppublish
SO - J Exp Bot. 2017 Jan 1;68(3):569-583. doi: 10.1093/jxb/erw474.
##### PUB RECORD #####
## 10.7554/elife.80741 36856086 PMC9991063 Lace, Su, et al., 2023 "Lace B, Su C, Invernot Perez D, Rodriguez-Franco M, Vernié T, Batzenschlager M, Egli S, Liu CW, Ott T. RPG acts as a central determinant for infectosome formation and cellular polarization during intracellular rhizobial infections. Elife. 2023 Mar 1;12:e80741. doi: 10.7554/eLife.80741. PMID: 36856086; PMCID: PMC9991063." ##
PMID- 36856086
OWN - NLM
STAT- MEDLINE
DCOM- 20230309
LR - 20230321
IS - 2050-084X (Electronic)
IS - 2050-084X (Linking)
VI - 12
DP - 2023 Mar 1
TI - RPG acts as a central determinant for infectosome formation and cellular
polarization during intracellular rhizobial infections.
LID - 10.7554/eLife.80741 [doi]
LID - e80741
AB - Host-controlled intracellular accommodation of nitrogen-fixing bacteria is
essential for the establishment of a functional Root Nodule Symbiosis (RNS). In
many host plants, this occurs via transcellular tubular structures (infection
threads - ITs) that extend across cell layers via polar tip-growth. Comparative
phylogenomic studies have identified RPG (RHIZOBIUM-DIRECTED POLAR GROWTH) among
the critical genetic determinants for bacterial infection. In Medicago
truncatula, RPG is required for effective IT progression within root hairs but
the cellular and molecular function of the encoded protein remains elusive. Here,
we show that RPG resides in the protein complex formed by the core endosymbiotic
components VAPYRIN (VPY) and LUMPY INFECTION (LIN) required for IT polar growth,
co-localizes with both VPY and LIN in IT tip- and perinuclear-associated puncta
of M. truncatula root hairs undergoing infection and is necessary for VPY
recruitment into these structures. Fluorescence Lifetime Imaging Microscopy
(FLIM) of phosphoinositide species during bacterial infection revealed that
functional RPG is required to sustain strong membrane polarization at the
advancing tip of the IT. In addition, loss of RPG functionality alters the
cytoskeleton-mediated connectivity between the IT tip and the nucleus and affects
the polar secretion of the cell wall modifying enzyme NODULE PECTATE LYASE (NPL).
Our results integrate RPG into a core host machinery required to support symbiont
accommodation, suggesting that its occurrence in plant host genomes is essential
to co-opt a multimeric protein module committed to endosymbiosis to sustain
IT-mediated bacterial infection.
CI - (c) 2023, Lace et al.
FAU - Lace, Beatrice
AU - Lace B
AUID- ORCID: 0000-0002-4732-573X
AD - University of Freiburg, Faculty of Biology, Freiburg, Germany.
FAU - Su, Chao
AU - Su C
AD - University of Freiburg, Faculty of Biology, Freiburg, Germany.
FAU - Invernot Perez, Daniel
AU - Invernot Perez D
AD - University of Freiburg, Faculty of Biology, Freiburg, Germany.
FAU - Rodriguez-Franco, Marta
AU - Rodriguez-Franco M
AUID- ORCID: 0000-0003-1183-2075
AD - University of Freiburg, Faculty of Biology, Freiburg, Germany.
FAU - Vernie, Tatiana
AU - Vernie T
AD - LRSV, Universite de Toulouse, CNRS, UPS, INP Toulouse, Castanet-Tolosan, France.
FAU - Batzenschlager, Morgane
AU - Batzenschlager M
AD - University of Freiburg, Faculty of Biology, Freiburg, Germany.
FAU - Egli, Sabrina
AU - Egli S
AD - University of Freiburg, Faculty of Biology, Freiburg, Germany.
FAU - Liu, Cheng-Wu
AU - Liu CW
AUID- ORCID: 0000-0002-6650-6245
AD - School of Life Sciences, Division of Life Sciences and Medicine, MOE Key
Laboratory for Membraneless Organelles and Cellular Dynamics, University of
Science and Technology of China, Hefei, China.
FAU - Ott, Thomas
AU - Ott T
AUID- ORCID: 0000-0002-4494-9811
AD - University of Freiburg, Faculty of Biology, Freiburg, Germany.
AD - CIBSS - Centre of Integrative Biological Signalling Studies, University of
Freiburg, Freiburg, Germany.
LA - eng
GR - OPP1172165/GATES/Bill & Melinda Gates Foundation/United States
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
PT - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20230301
PL - England
TA - Elife
JT - eLife
JID - 101579614
SB - IM
UOF - doi: 10.1101/2022.06.03.494689
MH - *Rhizobium
MH - Symbiosis
MH - *Nitrogen-Fixing Bacteria
MH - Cell Nucleus
MH - Cell Wall
PMC - PMC9991063
OTO - NOTNLM
OT - infection thread
OT - legume
OT - nodulation
OT - plant biology
OT - polarity
OT - rhizobia
OT - symbiosis
COIS- BL, CS, DI, MR, TV, MB, SE, CL, TO No competing interests declared
EDAT- 2023/03/02 06:00
MHDA- 2023/03/10 06:00
CRDT- 2023/03/01 05:54
PHST- 2022/06/01 00:00 [received]
PHST- 2023/02/21 00:00 [accepted]
PHST- 2023/03/02 06:00 [pubmed]
PHST- 2023/03/10 06:00 [medline]
PHST- 2023/03/01 05:54 [entrez]
AID - 80741 [pii]
AID - 10.7554/eLife.80741 [doi]
PST - epublish
SO - Elife. 2023 Mar 1;12:e80741. doi: 10.7554/eLife.80741.
##### PUB RECORD #####
## 10.1104/pp.109.143024 19789288 PMC2773094 Kuppusamy, Ivashuta, et al., 2009 "Kuppusamy KT, Ivashuta S, Bucciarelli B, Vance CP, Gantt JS, Vandenbosch KA. Knockdown of CELL DIVISION CYCLE16 reveals an inverse relationship between lateral root and nodule numbers and a link to auxin in Medicago truncatula. Plant Physiol. 2009 Nov;151(3):1155-66. doi: 10.1104/pp.109.143024. Epub 2009 Sep 29. PMID: 19789288; PMCID: PMC2773094." ##
PMID- 19789288
OWN - NLM
STAT- MEDLINE
DCOM- 20100127
LR - 20220318
IS - 1532-2548 (Electronic)
IS - 0032-0889 (Print)
IS - 0032-0889 (Linking)
VI - 151
IP - 3
DP - 2009 Nov
TI - Knockdown of CELL DIVISION CYCLE16 reveals an inverse relationship between
lateral root and nodule numbers and a link to auxin in Medicago truncatula.
PG - 1155-66
LID - 10.1104/pp.109.143024 [doi]
AB - The postembryonic development of lateral roots and nodules is a highly regulated
process. Recent studies suggest the existence of cross talk and interdependency
in the growth of these two organs. Although plant hormones, including auxin and
cytokinin, appear to be key players in coordinating this cross talk, very few
genes that cross-regulate root and nodule development have been uncovered so far.
This study reports that a homolog of CELL DIVISION CYCLE16 (CDC16), a core
component of the Anaphase Promoting Complex, is one of the key mediators in
controlling the overall number of lateral roots and nodules. A partial
suppression of this gene in Medicago truncatula leads to a decrease in number of
lateral roots and a 4-fold increase in number of nodules. The roots showing
lowered expression of MtCDC16 also show reduced sensitivity to phytohormone
auxin, thus providing a potential function of CDC16 in auxin signaling.
FAU - Kuppusamy, Kavitha T
AU - Kuppusamy KT
AD - Department of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108,
USA.
FAU - Ivashuta, Sergey
AU - Ivashuta S
FAU - Bucciarelli, Bruna
AU - Bucciarelli B
FAU - Vance, Carroll P
AU - Vance CP
FAU - Gantt, J Stephen
AU - Gantt JS
FAU - Vandenbosch, Kathryn A
AU - Vandenbosch KA
LA - eng
SI - GENBANK/GU075685
SI - GENBANK/GU075686
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
PT - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20090929
PL - United States
TA - Plant Physiol
JT - Plant physiology
JID - 0401224
RN - 0 (Cell Cycle Proteins)
RN - 0 (DNA, Plant)
RN - 0 (Indoleacetic Acids)
RN - 0 (Plant Growth Regulators)
RN - 0 (Plant Proteins)
SB - IM
MH - Amino Acid Sequence
MH - Cell Cycle Proteins/genetics/*metabolism
MH - DNA, Plant/genetics
MH - Gene Expression Regulation, Plant
MH - Gene Knockdown Techniques
MH - Indoleacetic Acids/*metabolism
MH - Medicago truncatula/cytology/*genetics/growth & development
MH - Molecular Sequence Data
MH - Oligonucleotide Array Sequence Analysis
MH - Plant Growth Regulators/metabolism
MH - Plant Proteins/genetics/*metabolism
MH - Plant Root Nodulation/*genetics
MH - Plants, Genetically Modified/cytology/genetics/growth & development
MH - RNA Interference
MH - Root Nodules, Plant/*growth & development
MH - Sequence Analysis, DNA
PMC - PMC2773094
EDAT- 2009/10/01 06:00
MHDA- 2010/01/28 06:00
CRDT- 2009/10/01 06:00
PHST- 2009/10/01 06:00 [entrez]
PHST- 2009/10/01 06:00 [pubmed]
PHST- 2010/01/28 06:00 [medline]
AID - pp.109.143024 [pii]
AID - 143024 [pii]
AID - 10.1104/pp.109.143024 [doi]
PST - ppublish
SO - Plant Physiol. 2009 Nov;151(3):1155-66. doi: 10.1104/pp.109.143024. Epub 2009 Sep
29.
##### PUB RECORD #####
## 10.1105/tpc.107.053975 18156218 PMC2217646 Kevei, Lougnon, et al., 2007 "Kevei Z, Lougnon G, Mergaert P, Horváth GV, Kereszt A, Jayaraman D, Zaman N, Marcel F, Regulski K, Kiss GB, Kondorosi A, Endre G, Kondorosi E, Ané JM. 3-hydroxy-3-methylglutaryl coenzyme a reductase 1 interacts with NORK and is crucial for nodulation in Medicago truncatula. Plant Cell. 2007 Dec;19(12):3974-89. doi: 10.1105/tpc.107.053975. Epub 2007 Dec 21. PMID: 18156218; PMCID: PMC2217646." ##
PMID- 18156218
OWN - NLM
STAT- MEDLINE
DCOM- 20080808
LR - 20181113
IS - 1040-4651 (Print)
IS - 1532-298X (Electronic)
IS - 1040-4651 (Linking)
VI - 19
IP - 12
DP - 2007 Dec
TI - 3-hydroxy-3-methylglutaryl coenzyme a reductase 1 interacts with NORK and is
crucial for nodulation in Medicago truncatula.
PG - 3974-89
AB - NORK in legumes encodes a receptor-like kinase that is required for Nod factor
signaling and root nodule development. Using Medicago truncatula NORK as bait in
a yeast two-hybrid assay, we identified 3-hydroxy-3-methylglutaryl CoA reductase
1 (Mt HMGR1) as a NORK interacting partner. HMGR1 belongs to a multigene family
in M. truncatula, and different HMGR isoforms are key enzymes in the mevalonate
biosynthetic pathway leading to the production of a diverse array of isoprenoid
compounds. Testing other HMGR members revealed a specific interaction between
NORK and HMGR1. Mutagenesis and deletion analysis showed that this interaction
requires the cytosolic active kinase domain of NORK and the cytosolic catalytic
domain of HMGR1. NORK homologs from Lotus japonicus and Sesbania rostrata also
interacted with Mt HMGR1, but homologous nonsymbiotic kinases of M. truncatula
did not. Pharmacological inhibition of HMGR activities decreased nodule number
and delayed nodulation, supporting the importance of the mevalonate pathway in
symbiotic development. Decreasing HMGR1 expression in M. truncatula transgenic
roots by RNA interference led to a dramatic decrease in nodulation, confirming
that HMGR1 is essential for nodule development. Recruitment of HMGR1 by NORK
could be required for production of specific isoprenoid compounds, such as
cytokinins, phytosteroids, or isoprenoid moieties involved in modification of
signaling proteins.
FAU - Kevei, Zoltan
AU - Kevei Z
AD - Institut des Sciences du Vegetal, Centre National de la Recherche Scientifique,
Unite Propre de Recherche 2355, 91198 Gif-sur-Yvette Cedex, France.
FAU - Lougnon, Geraldine
AU - Lougnon G
FAU - Mergaert, Peter
AU - Mergaert P
FAU - Horvath, Gabor V
AU - Horvath GV
FAU - Kereszt, Attila
AU - Kereszt A
FAU - Jayaraman, Dhileepkumar
AU - Jayaraman D
FAU - Zaman, Najia
AU - Zaman N
FAU - Marcel, Fabian
AU - Marcel F
FAU - Regulski, Krzysztof
AU - Regulski K
FAU - Kiss, Gyorgy B
AU - Kiss GB
FAU - Kondorosi, Adam
AU - Kondorosi A
FAU - Endre, Gabriella
AU - Endre G
FAU - Kondorosi, Eva
AU - Kondorosi E
FAU - Ane, Jean-Michel
AU - Ane JM
LA - eng
SI - GENBANK/AF492655
SI - GENBANK/AJ418369
SI - GENBANK/AY751547
SI - GENBANK/EU302813
SI - GENBANK/EU302814
SI - GENBANK/EU302815
SI - GENBANK/EU302816
SI - GENBANK/EU302817
PT - Journal Article
DEP - 20071221
PL - England
TA - Plant Cell
JT - The Plant cell
JID - 9208688
RN - 0 (Plant Proteins)
RN - 0 (Protein Isoforms)
RN - 9LHU78OQFD (Lovastatin)
RN - EC 1.1.1.- (Hydroxymethylglutaryl CoA Reductases)
SB - IM
MH - Amino Acid Sequence
MH - Enzyme Activation/drug effects
MH - Gene Expression Regulation, Plant/drug effects
MH - Hydroxymethylglutaryl CoA Reductases/genetics/*metabolism
MH - Immunoprecipitation
MH - In Situ Hybridization
MH - Lovastatin/pharmacology
MH - Medicago truncatula/genetics/*metabolism/microbiology
MH - Models, Genetic
MH - Molecular Sequence Data
MH - Mutation
MH - Plant Proteins/chemistry/genetics/*metabolism
MH - Protein Binding
MH - Protein Isoforms/chemistry/genetics/metabolism
MH - Protein Structure, Tertiary
MH - RNA Interference
MH - Reverse Transcriptase Polymerase Chain Reaction
MH - Root Nodules, Plant/genetics/*metabolism/microbiology
MH - Sequence Homology, Amino Acid
MH - Sinorhizobium meliloti/growth & development
MH - Symbiosis
MH - Two-Hybrid System Techniques
PMC - PMC2217646
EDAT- 2007/12/25 09:00
MHDA- 2008/08/09 09:00
CRDT- 2007/12/25 09:00
PHST- 2007/12/25 09:00 [pubmed]
PHST- 2008/08/09 09:00 [medline]
PHST- 2007/12/25 09:00 [entrez]
AID - tpc.107.053975 [pii]
AID - 053975 [pii]
AID - 10.1105/tpc.107.053975 [doi]
PST - ppublish
SO - Plant Cell. 2007 Dec;19(12):3974-89. doi: 10.1105/tpc.107.053975. Epub 2007 Dec
21.
##### PUB RECORD #####
## 10.1186/s13007-015-0053-y 25774204 PMC4359497 Oellrich, Walls et al., 2015 "Oellrich A, Walls RL, Cannon EK, Cannon SB, Cooper L, Gardiner J, Gkoutos GV, Harper L, He M, Hoehndorf R, Jaiswal P, Kalberer SR, Lloyd JP, Meinke D, Menda N, Moore L, Nelson RT, Pujar A, Lawrence CJ, Huala E. An ontology approach to comparative phenomics in plants. Plant Methods. 2015 Feb 25;11:10. doi: 10.1186/s13007-015-0053-y. PMID: 25774204; PMCID: PMC4359497." ##
PMID- 25774204
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150316
LR - 20220310
IS - 1746-4811 (Print)
IS - 1746-4811 (Electronic)
IS - 1746-4811 (Linking)
VI - 11
DP - 2015
TI - An ontology approach to comparative phenomics in plants.
PG - 10
LID - 10.1186/s13007-015-0053-y [doi]
LID - 10
AB - BACKGROUND: Plant phenotype datasets include many different types of data,
formats, and terms from specialized vocabularies. Because these datasets were
designed for different audiences, they frequently contain language and details
tailored to investigators with different research objectives and backgrounds.
Although phenotype comparisons across datasets have long been possible on a small
scale, comprehensive queries and analyses that span a broad set of reference
species, research disciplines, and knowledge domains continue to be severely
limited by the absence of a common semantic framework. RESULTS: We developed a
workflow to curate and standardize existing phenotype datasets for six plant
species, encompassing both model species and crop plants with established genetic
resources. Our effort focused on mutant phenotypes associated with genes of known
sequence in Arabidopsis thaliana (L.) Heynh. (Arabidopsis), Zea mays L. subsp.
mays (maize), Medicago truncatula Gaertn. (barrel medic or Medicago), Oryza
sativa L. (rice), Glycine max (L.) Merr. (soybean), and Solanum lycopersicum L.
(tomato). We applied the same ontologies, annotation standards, formats, and best
practices across all six species, thereby ensuring that the shared dataset could
be used for cross-species querying and semantic similarity analyses. Curated
phenotypes were first converted into a common format using taxonomically broad
ontologies such as the Plant Ontology, Gene Ontology, and Phenotype and Trait
Ontology. We then compared ontology-based phenotypic descriptions with an
existing classification system for plant phenotypes and evaluated our semantic
similarity dataset for its ability to enhance predictions of gene families,
protein functions, and shared metabolic pathways that underlie informative plant
phenotypes. CONCLUSIONS: The use of ontologies, annotation standards, shared
formats, and best practices for cross-taxon phenotype data analyses represents a
novel approach to plant phenomics that enhances the utility of model genetic
organisms and can be readily applied to species with fewer genetic resources and
less well-characterized genomes. In addition, these tools should enhance future
efforts to explore the relationships among phenotypic similarity, gene function,
and sequence similarity in plants, and to make genotype-to-phenotype predictions
relevant to plant biology, crop improvement, and potentially even human health.
FAU - Oellrich, Anika
AU - Oellrich A
AD - Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA
UK.
FAU - Walls, Ramona L
AU - Walls RL
AD - iPlant Collaborative, University of Arizona, 1657 E. Helen St., Tucson, Arizona
85721 USA.
FAU - Cannon, Ethalinda Ks
AU - Cannon EK
AD - Department of Electrical and Computer Engineering Iowa State University, 1018
Crop Informatics Lab, Ames, Iowa 50011 USA.
FAU - Cannon, Steven B
AU - Cannon SB
AD - USDA-ARS Corn Insects and Crop Genetics Research Unit, Iowa State University,
Crop Genome Informatics Lab, Iowa State University, Ames, IA 50011 USA.
AD - Department of Agronomy, Agronomy Hall, Iowa State University, Ames, IA 50010 USA.
FAU - Cooper, Laurel
AU - Cooper L
AD - Department of Botany and Plant Pathology, 2082 Cordley Hall, Oregon State
University, Corvallis, OR 97331 USA.
FAU - Gardiner, Jack
AU - Gardiner J
AD - Department of Genetics, Development and Cell Biology, Roy J Carver Co-Laboratory,
Iowa State University, Ames, IA 50010 USA.
FAU - Gkoutos, Georgios V
AU - Gkoutos GV
AD - Department of Computer Science, Aberystwyth University, Llandinam Building,
Aberystwyth, SY23 3DB UK.
FAU - Harper, Lisa
AU - Harper L
AD - USDA-ARS Corn Insects and Crop Genetics Research Unit, Iowa State University,
Crop Genome Informatics Lab, Iowa State University, Ames, IA 50011 USA.
FAU - He, Mingze
AU - He M
AD - Department of Genetics, Development and Cell Biology, Roy J Carver Co-Laboratory,
Iowa State University, Ames, IA 50010 USA.
FAU - Hoehndorf, Robert
AU - Hoehndorf R
AD - Computer, Electrical and Mathematical Sciences & Engineering Division and
Computational Bioscience Research Center, King Abdullah University of Science and
Technology, 4700 King Abdullah University of Science and Technology, P.O. Box
2882, Thuwal, 23955-6900 Kingdom of Saudi Arabia.
FAU - Jaiswal, Pankaj
AU - Jaiswal P
AD - Department of Botany and Plant Pathology, 2082 Cordley Hall, Oregon State
University, Corvallis, OR 97331 USA.
FAU - Kalberer, Scott R
AU - Kalberer SR
AD - USDA-ARS Corn Insects and Crop Genetics Research Unit, Iowa State University,
Crop Genome Informatics Lab, Iowa State University, Ames, IA 50011 USA.
FAU - Lloyd, John P
AU - Lloyd JP
AD - Department of Plant Biology, Michigan State University, 220 Trowbridge Rd, East
Lansing, MI 48824 USA.
FAU - Meinke, David
AU - Meinke D
AD - Department of Botany, Oklahoma State University, 301 Physical Sciences,
Stillwater, OK 74078 USA.
FAU - Menda, Naama
AU - Menda N
AD - Boyce Thompson Institute for Plant Research, 533 Tower Road, Ithaca, NY 14853
USA.
FAU - Moore, Laura
AU - Moore L
AD - Department of Botany and Plant Pathology, 2082 Cordley Hall, Oregon State
University, Corvallis, OR 97331 USA.
FAU - Nelson, Rex T
AU - Nelson RT
AD - USDA-ARS Corn Insects and Crop Genetics Research Unit, Iowa State University,
Crop Genome Informatics Lab, Iowa State University, Ames, IA 50011 USA.
FAU - Pujar, Anuradha
AU - Pujar A
AD - Boyce Thompson Institute for Plant Research, 533 Tower Road, Ithaca, NY 14853
USA.
FAU - Lawrence, Carolyn J
AU - Lawrence CJ
AD - Department of Agronomy, Agronomy Hall, Iowa State University, Ames, IA 50010 USA.
AD - Department of Genetics, Development and Cell Biology, Roy J Carver Co-Laboratory,
Iowa State University, Ames, IA 50010 USA.
FAU - Huala, Eva
AU - Huala E
AD - Phoenix Bioinformatics, 643 Bair Island Rd Suite 403, Redwood City, CA 94063 USA.
LA - eng
PT - Journal Article
DEP - 20150225
PL - England
TA - Plant Methods
JT - Plant methods
JID - 101245798
PMC - PMC4359497
EDAT- 2015/03/17 06:00
MHDA- 2015/03/17 06:01
CRDT- 2015/03/17 06:00
PHST- 2014/12/08 00:00 [received]
PHST- 2015/02/05 00:00 [accepted]
PHST- 2015/03/17 06:00 [entrez]
PHST- 2015/03/17 06:00 [pubmed]
PHST- 2015/03/17 06:01 [medline]
AID - 53 [pii]
AID - 10.1186/s13007-015-0053-y [doi]
PST - epublish
SO - Plant Methods. 2015 Feb 25;11:10. doi: 10.1186/s13007-015-0053-y. eCollection
2015.
##### PUB RECORD #####
## 10.1111/j.1469-8137.2012.04147.x 22530598 null Cheng, Peng, et al., 2012 "Cheng X, Peng J, Ma J, Tang Y, Chen R, Mysore KS, Wen J. NO APICAL MERISTEM (MtNAM) regulates floral organ identity and lateral organ separation in Medicago truncatula. New Phytol. 2012 Jul;195(1):71-84. doi: 10.1111/j.1469-8137.2012.04147.x. Epub 2012 Apr 24. PMID: 22530598." ##
PMID- 22530598
OWN - NLM
STAT- MEDLINE
DCOM- 20121009
LR - 20220331
IS - 1469-8137 (Electronic)
IS - 0028-646X (Linking)
VI - 195
IP - 1
DP - 2012 Jul
TI - NO APICAL MERISTEM (MtNAM) regulates floral organ identity and lateral organ
separation in Medicago truncatula.
PG - 71-84
LID - 10.1111/j.1469-8137.2012.04147.x [doi]
AB - * The CUP-SHAPED COTYLEDON (CUC)/NO APICAL MERISTEM (NAM) family of genes control
boundary formation and lateral organ separation, which is critical for proper
leaf and flower patterning. However, most downstream targets of CUC/NAM genes
remain unclear. * In a forward screen of the tobacco retrotransposon1 (Tnt1)
insertion population in Medicago truncatula, we isolated a weak allele of the
no-apical-meristem mutant mtnam-2. Meanwhile, we regenerated a mature plant from
the null allele mtnam-1. These materials allowed us to extensively characterize
the function of MtNAM and its downstream genes. * MtNAM is highly expressed in
vegetative shoot buds and inflorescence apices, specifically at boundaries
between the shoot apical meristem and leaf/flower primordia. Mature plants of the
regenerated null allele and the weak allele display remarkable floral phenotypes:
floral whorls and organ numbers are reduced and the floral organ identity is
compromised. Microarray and quantitative RT-PCR analyses revealed that all
classes of floral homeotic genes are down-regulated in mtnam mutants. Mutations
in MtNAM also lead to fused cotyledons and leaflets of the compound leaf as well
as a defective shoot apical meristem. * Our results revealed that MtNAM shares
the role of CUC/NAM family genes in lateral organ separation and compound leaf
development, and is also required for floral organ identity and development.
CI - (c) 2012 The Authors. New Phytologist (c) 2012 New Phytologist Trust.
FAU - Cheng, Xiaofei
AU - Cheng X
AD - Plant Biology Division, Samuel Roberts Noble Foundation, Ardmore, OK 73401, USA.
FAU - Peng, Jianling
AU - Peng J
FAU - Ma, Junying
AU - Ma J
FAU - Tang, Yuhong
AU - Tang Y
FAU - Chen, Rujin
AU - Chen R
FAU - Mysore, Kirankumar S
AU - Mysore KS
FAU - Wen, Jiangqi
AU - Wen J
LA - eng
SI - GENBANK/JF929904
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
PT - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20120424
PL - England
TA - New Phytol
JT - The New phytologist
JID - 9882884
RN - 0 (Plant Proteins)
RN - 0 (Retroelements)
SB - IM
MH - Cotyledon/anatomy & histology/genetics
MH - Flowers/genetics/*physiology
MH - *Gene Expression Regulation, Plant
MH - Genetic Association Studies
MH - Inflorescence/anatomy & histology/genetics
MH - Medicago truncatula/genetics/*physiology
MH - Meristem/*genetics/physiology
MH - Molecular Sequence Data
MH - Mutation
MH - Plant Leaves/genetics/growth & development
MH - Plant Proteins/*genetics/*metabolism
MH - Retroelements
EDAT- 2012/04/26 06:00
MHDA- 2012/10/10 06:00
CRDT- 2012/04/26 06:00
PHST- 2012/04/26 06:00 [entrez]
PHST- 2012/04/26 06:00 [pubmed]
PHST- 2012/10/10 06:00 [medline]
AID - 10.1111/j.1469-8137.2012.04147.x [doi]
PST - ppublish
SO - New Phytol. 2012 Jul;195(1):71-84. doi: 10.1111/j.1469-8137.2012.04147.x. Epub
2012 Apr 24.
##### PUB RECORD #####
## 10.3389/fpls.2015.00575 26284091 PMC4517396 Chen, Liu, et al., 2015 "Chen DS, Liu CW, Roy S, Cousins D, Stacey N, Murray JD. Identification of a core set of rhizobial infection genes using data from single cell-types. Front Plant Sci. 2015 Jul 28;6:575. doi: 10.3389/fpls.2015.00575. PMID: 26284091; PMCID: PMC4517396." ##
PMID- 26284091
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150818
LR - 20220129
IS - 1664-462X (Print)
IS - 1664-462X (Electronic)
IS - 1664-462X (Linking)
VI - 6
DP - 2015
TI - Identification of a core set of rhizobial infection genes using data from single
cell-types.
PG - 575
LID - 10.3389/fpls.2015.00575 [doi]
LID - 575
AB - Genome-wide expression studies on nodulation have varied in their scale from
entire root systems to dissected nodules or root sections containing nodule
primordia (NP). More recently efforts have focused on developing methods for
isolation of root hairs from infected plants and the application of laser-capture
microdissection technology to nodules. Here we analyze two published data sets to
identify a core set of infection genes that are expressed in the nodule and in
root hairs during infection. Among the genes identified were those encoding
phenylpropanoid biosynthesis enzymes including Chalcone-O-Methyltransferase which
is required for the production of the potent Nod gene inducer
4',4-dihydroxy-2-methoxychalcone. A promoter-GUS analysis in transgenic hairy
roots for two genes encoding Chalcone-O-Methyltransferase isoforms revealed their
expression in rhizobially infected root hairs and the nodule infection zone but
not in the nitrogen fixation zone. We also describe a group of Rhizobially
Induced Peroxidases whose expression overlaps with the production of superoxide
in rhizobially infected root hairs and in nodules and roots. Finally, we identify
a cohort of co-regulated transcription factors as candidate regulators of these
processes.
FAU - Chen, Da-Song
AU - Chen DS
AD - State Key Laboratory of Agricultural Microbiology, College of Life Science and
Technology, Huazhong Agricultural University, Wuhan China.
FAU - Liu, Cheng-Wu
AU - Liu CW
AD - John Innes Centre, Department of Cell and Developmental Biology, Norfolk UK.
FAU - Roy, Sonali
AU - Roy S
AD - John Innes Centre, Department of Cell and Developmental Biology, Norfolk UK.
FAU - Cousins, Donna
AU - Cousins D
AD - John Innes Centre, Department of Cell and Developmental Biology, Norfolk UK.
FAU - Stacey, Nicola
AU - Stacey N
AD - John Innes Centre, Department of Cell and Developmental Biology, Norfolk UK.
FAU - Murray, Jeremy D
AU - Murray JD
AD - John Innes Centre, Department of Cell and Developmental Biology, Norfolk UK.
LA - eng
GR - BB/G023832/1/BB_/Biotechnology and Biological Sciences Research Council/United
Kingdom
PT - Journal Article
DEP - 20150728
PL - Switzerland
TA - Front Plant Sci
JT - Frontiers in plant science
JID - 101568200
PMC - PMC4517396
OTO - NOTNLM
OT - CCAAT-box
OT - Nod factors
OT - infection threads
OT - infection zone
OT - medicarpin
OT - methoxychalcone
OT - nod genes
OT - nodulation
EDAT- 2015/08/19 06:00
MHDA- 2015/08/19 06:01
CRDT- 2015/08/19 06:00
PHST- 2015/05/12 00:00 [received]
PHST- 2015/07/13 00:00 [accepted]
PHST- 2015/08/19 06:00 [entrez]
PHST- 2015/08/19 06:00 [pubmed]
PHST- 2015/08/19 06:01 [medline]
AID - 10.3389/fpls.2015.00575 [doi]
PST - epublish
SO - Front Plant Sci. 2015 Jul 28;6:575. doi: 10.3389/fpls.2015.00575. eCollection
2015.
##### PUB RECORD #####
## 10.1105/tpc.15.00461 26672071 PMC4707452 Vernié, Kim, et al., 2015 "Vernié T, Kim J, Frances L, Ding Y, Sun J, Guan D, Niebel A, Gifford ML, de Carvalho-Niebel F, Oldroyd GE. The NIN Transcription Factor Coordinates Diverse Nodulation Programs in Different Tissues of the Medicago truncatula Root. Plant Cell. 2015 Dec;27(12):3410-24. doi: 10.1105/tpc.15.00461. Epub 2015 Dec 15. PMID: 26672071; PMCID: PMC4707452." ##
PMID- 26672071
OWN - NLM
STAT- MEDLINE
DCOM- 20170130
LR - 20210304
IS - 1532-298X (Electronic)
IS - 1040-4651 (Print)
IS - 1040-4651 (Linking)
VI - 27
IP - 12
DP - 2015 Dec
TI - The NIN Transcription Factor Coordinates Diverse Nodulation Programs in Different
Tissues of the Medicago truncatula Root.
PG - 3410-24
LID - 10.1105/tpc.15.00461 [doi]
AB - Biological nitrogen fixation in legumes occurs in nodules that are initiated in
the root cortex following Nod factor recognition at the root surface, and this
requires coordination of diverse developmental programs in these different
tissues. We show that while early Nod factor signaling associated with calcium
oscillations is limited to the root surface, the resultant activation of Nodule
Inception (NIN) in the root epidermis is sufficient to promote cytokinin
signaling and nodule organogenesis in the inner root cortex. NIN or a product of
its action must be associated with the transmission of a signal between the root
surface and the cortical cells where nodule organogenesis is initiated. NIN
appears to have distinct functions in the root epidermis and the root cortex. In
the epidermis, NIN restricts the extent of Early Nodulin 11 (ENOD11) expression
and does so through competitive inhibition of ERF Required for Nodulation (ERN1).
In contrast, NIN is sufficient to promote the expression of the cytokinin
receptor Cytokinin Response 1 (CRE1), which is restricted to the root cortex. Our
work in Medicago truncatula highlights the complexity of NIN action and places
NIN as a central player in the coordination of the symbiotic developmental
programs occurring in differing tissues of the root that combined are necessary
for a nitrogen-fixing symbiosis.
CI - (c) 2015 American Society of Plant Biologists. All rights reserved.
FAU - Vernie, Tatiana
AU - Vernie T
AUID- ORCID: 0000-0003-1387-6370
AD - Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH,
United Kingdom.
FAU - Kim, Jiyoung
AU - Kim J
AD - Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH,
United Kingdom.
FAU - Frances, Lisa
AU - Frances L
AD - Laboratoire des Interactions Plantes Microorganismes, CNRS-INRA 2594/441, F-31320
Castanet Tolosan, France.
FAU - Ding, Yiliang
AU - Ding Y
AD - Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH,
United Kingdom.
FAU - Sun, Jongho
AU - Sun J
AD - Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH,
United Kingdom.
FAU - Guan, Dian
AU - Guan D
AD - Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH,
United Kingdom.
FAU - Niebel, Andreas
AU - Niebel A
AUID- ORCID: 0000-0002-3402-8381
AD - Laboratoire des Interactions Plantes Microorganismes, CNRS-INRA 2594/441, F-31320
Castanet Tolosan, France.
FAU - Gifford, Miriam L
AU - Gifford ML
AUID- ORCID: 0000-0002-4005-2513
AD - School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
FAU - de Carvalho-Niebel, Fernanda
AU - de Carvalho-Niebel F
AD - Laboratoire des Interactions Plantes Microorganismes, CNRS-INRA 2594/441, F-31320
Castanet Tolosan, France.
FAU - Oldroyd, Giles E D
AU - Oldroyd GE
AD - Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH,
United Kingdom giles.oldroyd@jic.ac.uk.
LA - eng
GR - BB/H019502/1/BB_/Biotechnology and Biological Sciences Research Council/United
Kingdom
GR - BB/J001872/1/BB_/Biotechnology and Biological Sciences Research Council/United
Kingdom
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20151215
PL - England
TA - Plant Cell
JT - The Plant cell
JID - 9208688
RN - 0 (Cytokinins)
RN - 0 (ENOD11 protein, Medicago truncatula)
RN - 0 (NIN protein, Lotus japonicus)
RN - 0 (Plant Growth Regulators)
RN - 0 (Plant Proteins)
RN - 0 (Transcription Factors)
RN - SY7Q814VUP (Calcium)
SB - IM
MH - Calcium/metabolism
MH - Cytokinins/metabolism
MH - Gene Expression Regulation, Plant
MH - Genes, Reporter
MH - Medicago truncatula/cytology/*genetics/physiology
MH - Nitrogen Fixation
MH - Plant Growth Regulators/metabolism
MH - Plant Proteins/genetics/*metabolism
MH - Plant Root Nodulation
MH - Plant Roots/cytology/genetics/metabolism/physiology
MH - Plants, Genetically Modified
MH - Root Nodules, Plant/cytology/genetics/physiology
MH - *Signal Transduction
MH - Sinorhizobium meliloti/*physiology
MH - *Symbiosis
MH - Tobacco/cytology/genetics/physiology
MH - Transcription Factors/genetics/*metabolism
PMC - PMC4707452
EDAT- 2015/12/17 06:00
MHDA- 2017/01/31 06:00
CRDT- 2015/12/17 06:00
PHST- 2015/05/21 00:00 [received]
PHST- 2015/11/20 00:00 [accepted]
PHST- 2015/12/17 06:00 [entrez]
PHST- 2015/12/17 06:00 [pubmed]
PHST- 2017/01/31 06:00 [medline]
AID - tpc.15.00461 [pii]
AID - TPC201500461RAR2 [pii]
AID - 10.1105/tpc.15.00461 [doi]
PST - ppublish
SO - Plant Cell. 2015 Dec;27(12):3410-24. doi: 10.1105/tpc.15.00461. Epub 2015 Dec 15.
##### PUB RECORD #####
## 10.1094/mpmi.2000.13.7.763 10875337 null Salzer, Bonanomi, et al., 2000 "Salzer P, Bonanomi A, Beyer K, Vögeli-Lange R, Aeschbacher RA, Lange J, Wiemken A, Kim D, Cook DR, Boller T. Differential expression of eight chitinase genes in Medicago truncatula roots during mycorrhiza formation, nodulation, and pathogen infection. Mol Plant Microbe Interact. 2000 Jul;13(7):763-77. doi: 10.1094/MPMI.2000.13.7.763. PMID: 10875337." ##
PMID- 10875337
OWN - NLM
STAT- MEDLINE
DCOM- 20001026
LR - 20161124
IS - 0894-0282 (Print)
IS - 0894-0282 (Linking)
VI - 13
IP - 7
DP - 2000 Jul
TI - Differential expression of eight chitinase genes in Medicago truncatula roots
during mycorrhiza formation, nodulation, and pathogen infection.
PG - 763-77
AB - Expression of eight different chitinase genes, representing members of five
chitinase classes, was studied in Medicago truncatula roots during formation of
arbuscular mycorrhiza with Glomus intraradices, nodulation with Rhizobium
meliloti, and pathogen attack by Phytophthora megasperma f. sp. medicaginis,
Fusarium solani f. sp. phaseoli (compatible interactions with root rot symptoms),
Ascochyta pisi (compatible, symptomless), and F. solani f. sp. pisi
(incompatible, nonhost interaction). In the compatible plant-pathogen
interactions, expression of class I, II, and IV chitinase genes was enhanced. The
same genes were induced during nodulation. Transcripts of class I and II
chitinase genes accumulated transiently during early stages of the interaction,
and transcripts of the class IV chitinase gene accumulated in mature nodules. The
pattern of chitinase gene expression in mycorrhizal roots was markedly different:
Expression of class I, II, and IV chitinase genes was not enhanced, whereas
expression of three class III chitinase genes, with almost no basal expression,
was strongly induced. Two of these three (Mtchitinase III-2 and Mtchitinase
III-3) were not induced at all in interactions with pathogens and rhizobia. Thus,
the expression of two mycorrhiza-specific class III chitinase genes can be
considered a hallmark for the establishment of arbuscular mycorrhiza in Medicago
truncatula.
FAU - Salzer, P
AU - Salzer P
AD - Botanisches Institut der Universitat Basel, Switzerland. Peter.Salzer@unibas.ch
FAU - Bonanomi, A
AU - Bonanomi A
FAU - Beyer, K
AU - Beyer K
FAU - Vogeli-Lange, R
AU - Vogeli-Lange R
FAU - Aeschbacher, R A
AU - Aeschbacher RA
FAU - Lange, J
AU - Lange J
FAU - Wiemken, A
AU - Wiemken A
FAU - Kim, D
AU - Kim D
FAU - Cook, D R
AU - Cook DR
FAU - Boller, T
AU - Boller T
LA - eng
SI - GENBANK/AF167322
SI - GENBANK/AF167323
SI - GENBANK/AF167324
SI - GENBANK/AF167325
SI - GENBANK/AF167326
SI - GENBANK/AF167327
SI - GENBANK/AF167328
SI - GENBANK/AF167329
SI - GENBANK/AJ238651
SI - GENBANK/AJ245511
SI - GENBANK/AJ245512
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
PL - United States
TA - Mol Plant Microbe Interact
JT - Molecular plant-microbe interactions : MPMI
JID - 9107902
RN - 0 (DNA Primers)
RN - 0 (Isoenzymes)
RN - 0 (Ubiquitins)
RN - EC 3.2.1.14 (Chitinases)
SB - IM
MH - Amino Acid Sequence
MH - Base Sequence
MH - Chitinases/biosynthesis/chemistry/*genetics
MH - DNA Primers
MH - Enzyme Induction
MH - Fusarium/*pathogenicity
MH - Gene Expression Regulation, Enzymologic
MH - *Gene Expression Regulation, Plant
MH - Isoenzymes/biosynthesis/chemistry/genetics
MH - Medicago sativa/enzymology/*genetics/*microbiology
MH - Molecular Sequence Data
MH - Phytophthora/*pathogenicity
MH - Plant Diseases
MH - Plant Roots/enzymology/microbiology
MH - Polymerase Chain Reaction
MH - Sequence Alignment
MH - Sequence Homology, Nucleic Acid
MH - Ubiquitins/genetics
EDAT- 2000/06/30 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/06/30 11:00
PHST- 2000/06/30 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/06/30 11:00 [entrez]
AID - 10.1094/MPMI.2000.13.7.763 [doi]
PST - ppublish
SO - Mol Plant Microbe Interact. 2000 Jul;13(7):763-77. doi:
10.1094/MPMI.2000.13.7.763.
##### PUB RECORD #####
## 10.1104/pp.108.125062 18790999 PMC2577242 Floss, Schliemann, et al., 2008 "Floss DS, Schliemann W, Schmidt J, Strack D, Walter MH. RNA interference-mediated repression of MtCCD1 in mycorrhizal roots of Medicago truncatula causes accumulation of C27 apocarotenoids, shedding light on the functional role of CCD1. Plant Physiol. 2008 Nov;148(3):1267-82. doi: 10.1104/pp.108.125062. Epub 2008 Sep 12. PMID: 18790999; PMCID: PMC2577242." ##
PMID- 18790999
OWN - NLM
STAT- MEDLINE
DCOM- 20090102
LR - 20211020
IS - 0032-0889 (Print)
IS - 1532-2548 (Electronic)
IS - 0032-0889 (Linking)
VI - 148
IP - 3
DP - 2008 Nov
TI - RNA interference-mediated repression of MtCCD1 in mycorrhizal roots of Medicago
truncatula causes accumulation of C27 apocarotenoids, shedding light on the
functional role of CCD1.
PG - 1267-82
LID - 10.1104/pp.108.125062 [doi]
AB - Tailoring carotenoids by plant carotenoid cleavage dioxygenases (CCDs) generates
various bioactive apocarotenoids. Recombinant CCD1 has been shown to catalyze
symmetrical cleavage of C(40) carotenoid substrates at 9,10 and 9',10' positions.
The actual substrate(s) of the enzyme in planta, however, is still unknown. In
this study, we have carried out RNA interference (RNAi)-mediated repression of a
Medicago truncatula CCD1 gene in hairy roots colonized by the arbuscular
mycorrhizal (AM) fungus Glomus intraradices. As a consequence, the normal
AM-mediated accumulation of apocarotenoids (C(13) cyclohexenone and C(14)
mycorradicin derivatives) was differentially modified. Mycorradicin derivatives
were strongly reduced to 3% to 6% of the controls, while the cyclohexenone
derivatives were only reduced to 30% to 47%. Concomitantly, a yellow-orange color
appeared in RNAi roots. Based on ultraviolet light spectra and mass spectrometry
analyses, the new compounds are C(27) apocarotenoic acid derivatives. These
metabolic alterations did not lead to major changes in molecular markers of the
AM symbiosis, although a moderate shift to more degenerating arbuscules was
observed in RNAi roots. The unexpected outcome of the RNAi approach suggests
C(27) apocarotenoids as the major substrates of CCD1 in mycorrhizal root cells.
Moreover, literature data implicate C(27) apocarotenoid cleavage as the general
functional role of CCD1 in planta. A revised scheme of plant carotenoid cleavage
in two consecutive steps is proposed, in which CCD1 catalyzes only the second
step in the cytosol (C(27)-->C(14)+C(13)), while the first step
(C(40)-->C(27)+C(13)) may be catalyzed by CCD7 and/or CCD4 inside plastids.
FAU - Floss, Daniela S
AU - Floss DS
AD - Leibniz-Institut fur Pflanzenbiochemie, Abteilung Sekundarstoffwechsel , D-06120
Halle, Germany.
FAU - Schliemann, Willibald
AU - Schliemann W
FAU - Schmidt, Jurgen
AU - Schmidt J
FAU - Strack, Dieter
AU - Strack D
FAU - Walter, Michael H
AU - Walter MH
LA - eng
SI - GENBANK/FM204879
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20080912
PL - United States
TA - Plant Physiol
JT - Plant physiology
JID - 0401224
RN - 0 (DNA Primers)
RN - 0 (DNA, Complementary)
RN - 0 (RNA, Messenger)
RN - 36-88-4 (Carotenoids)
RN - EC 1.13.11.- (Dioxygenases)
RN - EC 1.13.11.- (carotenoid cleavage dioxygenase 1)
SB - IM
MH - Base Sequence
MH - Carotenoids/*metabolism
MH - Chromatography, High Pressure Liquid
MH - Cloning, Molecular
MH - DNA Primers
MH - DNA, Complementary
MH - Dioxygenases/*genetics/metabolism
MH - *Genes, Plant
MH - Mass Spectrometry
MH - Medicago truncatula/genetics/*metabolism
MH - Molecular Sequence Data
MH - Plant Roots/*enzymology
MH - *RNA Interference
MH - RNA, Messenger/genetics
MH - Reverse Transcriptase Polymerase Chain Reaction
PMC - PMC2577242
EDAT- 2008/09/16 09:00
MHDA- 2009/01/03 09:00
CRDT- 2008/09/16 09:00
PHST- 2008/09/16 09:00 [pubmed]
PHST- 2009/01/03 09:00 [medline]
PHST- 2008/09/16 09:00 [entrez]
AID - pp.108.125062 [pii]
AID - 125062 [pii]
AID - 10.1104/pp.108.125062 [doi]
PST - ppublish
SO - Plant Physiol. 2008 Nov;148(3):1267-82. doi: 10.1104/pp.108.125062. Epub 2008 Sep
12.
##### PUB RECORD #####
## 10.1073/pnas.2205920119 35972963 PMC9407390 Liu, Lin, et al., 2022 "Liu H, Lin JS, Luo Z, Sun J, Huang X, Yang Y, Xu J, Wang YF, Zhang P, Oldroyd GED, Xie F. Constitutive activation of a nuclear-localized calcium channel complex in Medicago truncatula. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2205920119. doi: 10.1073/pnas.2205920119. Epub 2022 Aug 16. PMID: 35972963; PMCID: PMC9407390." ##
PMID- 35972963
OWN - NLM
STAT- MEDLINE
DCOM- 20220818
LR - 20230217
IS - 1091-6490 (Electronic)
IS - 0027-8424 (Print)
IS - 0027-8424 (Linking)
VI - 119
IP - 34
DP - 2022 Aug 23
TI - Constitutive activation of a nuclear-localized calcium channel complex in
Medicago truncatula.
PG - e2205920119
LID - 10.1073/pnas.2205920119 [doi]
LID - e2205920119
AB - Nuclear Ca(2+) oscillations allow symbiosis signaling, facilitating plant
recognition of beneficial microsymbionts, nitrogen-fixing rhizobia, and
nutrient-capturing arbuscular mycorrhizal fungi. Two classes of channels, DMI1
and CNGC15, in a complex on the nuclear membrane, coordinate symbiotic Ca(2+)
oscillations. However, the mechanism of Ca(2+) signature generation is unknown.
Here, we demonstrate spontaneous activation of this channel complex, through
gain-of-function mutations in DMI1, leading to spontaneous nuclear Ca(2+)
oscillations and spontaneous nodulation, in a CNGC15-dependent manner. The
mutations destabilize a hydrogen-bond or salt-bridge network between two RCK
domains, with the resultant structural changes, alongside DMI1 cation
permeability, activating the channel complex. This channel complex was
reconstituted in human HEK293T cell lines, with the resultant calcium influx
enhanced by autoactivated DMI1 and CNGC15s. Our results demonstrate the mode of
activation of this nuclear channel complex, show that DMI1 and CNGC15 are
sufficient to create oscillatory Ca(2+) signals, and provide insights into its
native mode of induction.
FAU - Liu, Haiyue
AU - Liu H
AUID- ORCID: 0000-0001-9009-2153
AD - National Key Laboratory of Plant Molecular Genetics,Chinese Academy of Sciences
Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant
Physiology and Ecology, Chinese Academy of Sciences, Shanghai, 200032, China.
AD - University of the Chinese Academy of Sciences, Beijing, 100049, China.
FAU - Lin, Jie-Shun
AU - Lin JS
AUID- ORCID: 0000-0002-3726-0303
AD - National Key Laboratory of Plant Molecular Genetics,Chinese Academy of Sciences
Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant
Physiology and Ecology, Chinese Academy of Sciences, Shanghai, 200032, China.
AD - University of the Chinese Academy of Sciences, Beijing, 100049, China.
FAU - Luo, Zhenpeng
AU - Luo Z
AUID- ORCID: 0000-0002-4512-8505
AD - National Key Laboratory of Plant Molecular Genetics,Chinese Academy of Sciences
Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant
Physiology and Ecology, Chinese Academy of Sciences, Shanghai, 200032, China.
AD - University of the Chinese Academy of Sciences, Beijing, 100049, China.
FAU - Sun, Jongho
AU - Sun J
AUID- ORCID: 0000-0002-3705-3072
AD - Sainsbury Laboratory, University of Cambridge, 47 Bateman Street, Cambridge, CB2
1LR, United Kingdom.
FAU - Huang, Xiaowei
AU - Huang X
AUID- ORCID: 0000-0001-9964-687X
AD - National Key Laboratory of Plant Molecular Genetics,Chinese Academy of Sciences
Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant
Physiology and Ecology, Chinese Academy of Sciences, Shanghai, 200032, China.
AD - University of the Chinese Academy of Sciences, Beijing, 100049, China.
FAU - Yang, Yang
AU - Yang Y
AD - National Key Laboratory of Plant Molecular Genetics,Chinese Academy of Sciences
Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant
Physiology and Ecology, Chinese Academy of Sciences, Shanghai, 200032, China.
AD - University of the Chinese Academy of Sciences, Beijing, 100049, China.
FAU - Xu, Ji
AU - Xu J
AD - National Key Laboratory of Plant Molecular Genetics,Chinese Academy of Sciences
Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant
Physiology and Ecology, Chinese Academy of Sciences, Shanghai, 200032, China.
FAU - Wang, Yong-Fei
AU - Wang YF
AUID- ORCID: 0000-0003-3139-7701
AD - National Key Laboratory of Plant Molecular Genetics,Chinese Academy of Sciences
Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant
Physiology and Ecology, Chinese Academy of Sciences, Shanghai, 200032, China.
FAU - Zhang, Peng
AU - Zhang P
AUID- ORCID: 0000-0003-0408-2923
AD - National Key Laboratory of Plant Molecular Genetics,Chinese Academy of Sciences
Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant
Physiology and Ecology, Chinese Academy of Sciences, Shanghai, 200032, China.
FAU - Oldroyd, Giles E D
AU - Oldroyd GED
AUID- ORCID: 0000-0002-5245-6355
AD - Sainsbury Laboratory, University of Cambridge, 47 Bateman Street, Cambridge, CB2
1LR, United Kingdom.
FAU - Xie, Fang
AU - Xie F
AUID- ORCID: 0000-0002-0530-1430
AD - National Key Laboratory of Plant Molecular Genetics,Chinese Academy of Sciences
Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant
Physiology and Ecology, Chinese Academy of Sciences, Shanghai, 200032, China.
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20220816
PL - United States
TA - Proc Natl Acad Sci U S A
JT - Proceedings of the National Academy of Sciences of the United States of America
JID - 7505876
RN - 0 (Calcium Channels)
RN - 0 (Plant Proteins)
RN - SY7Q814VUP (Calcium)
SB - IM
MH - Calcium/metabolism
MH - *Calcium Channels/genetics/metabolism
MH - *Calcium Signaling/physiology
MH - Cell Nucleus/metabolism
MH - Gain of Function Mutation
MH - Gene Expression Regulation, Plant
MH - HEK293 Cells
MH - Humans
MH - *Medicago truncatula/genetics/physiology
MH - *Plant Proteins/genetics/metabolism
MH - *Plant Root Nodulation/genetics/physiology
MH - *Plant Roots/genetics/physiology
MH - Symbiosis/physiology
PMC - PMC9407390
OTO - NOTNLM
OT - CNGC15
OT - DMI1
OT - NF signaling
OT - calcium channel
OT - nuclear calcium spiking
COIS- The authors declare no competing interest.
EDAT- 2022/08/17 06:00
MHDA- 2022/08/19 06:00
CRDT- 2022/08/16 13:42
PHST- 2022/08/16 13:42 [entrez]
PHST- 2022/08/17 06:00 [pubmed]
PHST- 2022/08/19 06:00 [medline]
AID - 202205920 [pii]
AID - 10.1073/pnas.2205920119 [doi]
PST - ppublish
SO - Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2205920119. doi:
10.1073/pnas.2205920119. Epub 2022 Aug 16.
##### PUB RECORD #####
## 10.1111/nph.12198 23432463 null Rey, Nars, et al., 2013 "Rey T, Nars A, Bonhomme M, Bottin A, Huguet S, Balzergue S, Jardinaud MF, Bono JJ, Cullimore J, Dumas B, Gough C, Jacquet C. NFP, a LysM protein controlling Nod factor perception, also intervenes in Medicago truncatula resistance to pathogens. New Phytol. 2013 May;198(3):875-886. doi: 10.1111/nph.12198. Epub 2013 Feb 25. PMID: 23432463." ##
PMID- 23432463
OWN - NLM
STAT- MEDLINE
DCOM- 20131125
LR - 20211203
IS - 1469-8137 (Electronic)
IS - 0028-646X (Linking)
VI - 198
IP - 3
DP - 2013 May
TI - NFP, a LysM protein controlling Nod factor perception, also intervenes in
Medicago truncatula resistance to pathogens.
PG - 875-886
LID - 10.1111/nph.12198 [doi]
AB - Plant LysM proteins control the perception of microbial-derived
N-acetylglucosamine compounds for the establishment of symbiosis or activation of
plant immunity. This raises questions about how plants, and notably legumes, can
differentiate friends and foes using similar molecular actors and whether any
receptors can intervene in both symbiosis and resistance. To study this question,
nfp and lyk3 LysM-receptor like kinase mutants of Medicago truncatula that are
affected in the early steps of nodulation, were analysed following inoculation
with Aphanomyces euteiches, a root oomycete. The role of NFP in this interaction
was further analysed by overexpression of NFP and by transcriptome analyses. nfp,
but not lyk3, mutants were significantly more susceptible than wildtype plants to
A. euteiches, whereas NFP overexpression increased resistance. Transcriptome
analyses on A. euteiches inoculation showed that mutation in the NFP gene led to
significant changes in the expression of c. 500 genes, notably involved in cell
dynamic processes previously associated with resistance to pathogen penetration.
nfp mutants also showed an increased susceptibility to the fungus Colletotrichum
trifolii. These results demonstrate that NFP intervenes in M. truncatula
immunity, suggesting an unsuspected role for NFP in the perception of pathogenic
signals.
CI - (c) 2013 The Authors. New Phytologist (c) 2013 New Phytologist Trust.
FAU - Rey, Thomas
AU - Rey T
AD - Universite de Toulouse, UPS, UMR 5546, Laboratoire de Recherche en Sciences
Vegetales, BP42617, Auzeville, F-31326, Castanet-Tolosan, France.
AD - CNRS, UMR 5546, Laboratoire de Recherche en Sciences Vegetales, BP42617,
Auzeville, F-31326, Castanet-Tolosan, France.
FAU - Nars, Amaury
AU - Nars A
AD - Universite de Toulouse, UPS, UMR 5546, Laboratoire de Recherche en Sciences
Vegetales, BP42617, Auzeville, F-31326, Castanet-Tolosan, France.
AD - CNRS, UMR 5546, Laboratoire de Recherche en Sciences Vegetales, BP42617,
Auzeville, F-31326, Castanet-Tolosan, France.
FAU - Bonhomme, Maxime
AU - Bonhomme M
AD - Universite de Toulouse, UPS, UMR 5546, Laboratoire de Recherche en Sciences
Vegetales, BP42617, Auzeville, F-31326, Castanet-Tolosan, France.
AD - CNRS, UMR 5546, Laboratoire de Recherche en Sciences Vegetales, BP42617,
Auzeville, F-31326, Castanet-Tolosan, France.
FAU - Bottin, Arnaud
AU - Bottin A
AD - Universite de Toulouse, UPS, UMR 5546, Laboratoire de Recherche en Sciences
Vegetales, BP42617, Auzeville, F-31326, Castanet-Tolosan, France.
AD - CNRS, UMR 5546, Laboratoire de Recherche en Sciences Vegetales, BP42617,
Auzeville, F-31326, Castanet-Tolosan, France.
FAU - Huguet, Stephanie
AU - Huguet S
AD - Unite de Recherche en Genomique Vegetale (URGV), UMR INRA 1165, Universite d'Evry
Val d'Essonne, ERL CNRS 8196, CP 5708, F-91057, Evry Cedex, France.
FAU - Balzergue, Sandrine
AU - Balzergue S
AD - Unite de Recherche en Genomique Vegetale (URGV), UMR INRA 1165, Universite d'Evry
Val d'Essonne, ERL CNRS 8196, CP 5708, F-91057, Evry Cedex, France.
FAU - Jardinaud, Marie-Francoise
AU - Jardinaud MF
AD - INRA, Laboratoire des Interactions Plantes-Microorganismes (LIPM), UMR441,
F-31326, Castanet-Tolosan, France.
FAU - Bono, Jean-Jacques
AU - Bono JJ
AD - INRA, Laboratoire des Interactions Plantes-Microorganismes (LIPM), UMR441,
F-31326, Castanet-Tolosan, France.
AD - CNRS, Laboratoire des Interactions Plantes-Microorganismes (LIPM), UMR2594,
F-31326, Castanet-Tolosan, France.
FAU - Cullimore, Julie
AU - Cullimore J
AD - INRA, Laboratoire des Interactions Plantes-Microorganismes (LIPM), UMR441,
F-31326, Castanet-Tolosan, France.
AD - CNRS, Laboratoire des Interactions Plantes-Microorganismes (LIPM), UMR2594,
F-31326, Castanet-Tolosan, France.
FAU - Dumas, Bernard
AU - Dumas B
AD - Universite de Toulouse, UPS, UMR 5546, Laboratoire de Recherche en Sciences
Vegetales, BP42617, Auzeville, F-31326, Castanet-Tolosan, France.
AD - CNRS, UMR 5546, Laboratoire de Recherche en Sciences Vegetales, BP42617,
Auzeville, F-31326, Castanet-Tolosan, France.
FAU - Gough, Clare
AU - Gough C
AD - INRA, Laboratoire des Interactions Plantes-Microorganismes (LIPM), UMR441,
F-31326, Castanet-Tolosan, France.
AD - CNRS, Laboratoire des Interactions Plantes-Microorganismes (LIPM), UMR2594,
F-31326, Castanet-Tolosan, France.
FAU - Jacquet, Christophe
AU - Jacquet C
AD - Universite de Toulouse, UPS, UMR 5546, Laboratoire de Recherche en Sciences
Vegetales, BP42617, Auzeville, F-31326, Castanet-Tolosan, France.
AD - CNRS, UMR 5546, Laboratoire de Recherche en Sciences Vegetales, BP42617,
Auzeville, F-31326, Castanet-Tolosan, France.
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20130225
PL - England
TA - New Phytol
JT - The New phytologist
JID - 9882884
RN - 0 (Plant Proteins)
RN - EC 2.7.11.1 (Protein Serine-Threonine Kinases)
SB - IM
MH - Aphanomyces/pathogenicity/physiology
MH - Colletotrichum/*pathogenicity
MH - Disease Resistance/genetics
MH - Gene Expression Profiling
MH - Gene Expression Regulation, Plant
MH - *Host-Pathogen Interactions
MH - Medicago truncatula/genetics/*metabolism/*microbiology
MH - Mutation
MH - Plant Diseases/genetics/microbiology
MH - Plant Proteins/genetics/*metabolism
MH - Plant Roots/metabolism/microbiology
MH - Plants, Genetically Modified
MH - Protein Serine-Threonine Kinases/genetics/metabolism
MH - Symbiosis/physiology
EDAT- 2013/02/26 06:00
MHDA- 2013/12/16 06:00
CRDT- 2013/02/26 06:00
PHST- 2012/11/21 00:00 [received]
PHST- 2013/01/17 00:00 [accepted]
PHST- 2013/02/26 06:00 [entrez]
PHST- 2013/02/26 06:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
AID - 10.1111/nph.12198 [doi]
PST - ppublish
SO - New Phytol. 2013 May;198(3):875-886. doi: 10.1111/nph.12198. Epub 2013 Feb 25.
##### PUB RECORD #####
## 10.1104/pp.18.01588 30782966 PMC6501087 Laffont, Huault, et al., 2019 "Laffont C, Huault E, Gautrat P, Endre G, Kalo P, Bourion V, Duc G, Frugier F. Independent Regulation of Symbiotic Nodulation by the SUNN Negative and CRA2 Positive Systemic Pathways. Plant Physiol. 2019 May;180(1):559-570. doi: 10.1104/pp.18.01588. Epub 2019 Feb 19. PMID: 30782966; PMCID: PMC6501087." ##
PMID- 30782966
OWN - NLM
STAT- MEDLINE
DCOM- 20200226
LR - 20200501
IS - 1532-2548 (Electronic)
IS - 0032-0889 (Print)
IS - 0032-0889 (Linking)
VI - 180
IP - 1
DP - 2019 May
TI - Independent Regulation of Symbiotic Nodulation by the SUNN Negative and CRA2
Positive Systemic Pathways.
PG - 559-570
LID - 10.1104/pp.18.01588 [doi]
AB - Plant systemic signaling pathways allow the integration and coordination of shoot
and root organ metabolism and development at the whole-plant level depending on
nutrient availability. In legumes, two systemic pathways have been reported in
the Medicago truncatula model to regulate root nitrogen-fixing symbiotic
nodulation. Both pathways involve leucine-rich repeat receptor-like kinases
acting in shoots and proposed to perceive signaling peptides produced in roots
depending on soil nutrient availability. In this study, we characterized in the
M. truncatula Jemalong A17 genotype a mutant allelic series affecting the Compact
Root Architecture2 (CRA2) receptor. These analyses revealed that this pathway
acts systemically from shoots to positively regulate nodulation and is required
for the activity of carboxyl-terminally encoded peptides (CEPs). In addition, we
generated a double mutant to test genetic interactions of the CRA2 systemic
pathway with the CLAVATA3/EMBRYO SURROUNDING REGION peptide (CLE)/Super Numeric
Nodule (SUNN) receptor systemic pathway negatively regulating nodule number from
shoots, which revealed an intermediate nodule number phenotype close to the wild
type. Finally, we showed that the nitrate inhibition of nodule numbers was
observed in cra2 mutants but not in sunn and cra2 sunn mutants. Overall, these
results suggest that CEP/CRA2 and CLE/SUNN systemic pathways act independently
from shoots to regulate nodule numbers.
CI - (c) 2019 American Society of Plant Biologists. All Rights Reserved.
FAU - Laffont, Carole
AU - Laffont C
AUID- ORCID: 0000-0002-8447-1736
AD - Institute of Plant Sciences Paris-Saclay, Centre National de la Recherche
Scientifique, Universite Paris Sud, Universite Paris Diderot, Institut National
de la Recherche Agronomique, Universite d'Evry, Universite Paris-Saclay, 91190
Gif-sur-Yvette, France.
FAU - Huault, Emeline
AU - Huault E
AD - Institute of Plant Sciences Paris-Saclay, Centre National de la Recherche
Scientifique, Universite Paris Sud, Universite Paris Diderot, Institut National
de la Recherche Agronomique, Universite d'Evry, Universite Paris-Saclay, 91190
Gif-sur-Yvette, France.
FAU - Gautrat, Pierre
AU - Gautrat P
AD - Institute of Plant Sciences Paris-Saclay, Centre National de la Recherche
Scientifique, Universite Paris Sud, Universite Paris Diderot, Institut National
de la Recherche Agronomique, Universite d'Evry, Universite Paris-Saclay, 91190
Gif-sur-Yvette, France.
FAU - Endre, Gabriella
AU - Endre G
AD - Institute of Plant Biology, Biological Research Centre, 6726 Szeged, Hungary.
FAU - Kalo, Peter
AU - Kalo P
AUID- ORCID: 0000-0002-0404-8904
AD - National Agricultural and Innovation Center, Agricultural Biotechnology
Institute, 2100 Godollo, Hungary.
FAU - Bourion, Virginie
AU - Bourion V
AD - Agroecologie, Institut National de la Recherche Agronomique, AgroSup Dijon,
Universite Bourgogne Franche-Comte, 21065 Dijon, France.
FAU - Duc, Gerard
AU - Duc G
AUID- ORCID: 0000-0002-2921-3152
AD - Agroecologie, Institut National de la Recherche Agronomique, AgroSup Dijon,
Universite Bourgogne Franche-Comte, 21065 Dijon, France.
FAU - Frugier, Florian
AU - Frugier F
AUID- ORCID: 0000-0002-9783-7418
AD - Institute of Plant Sciences Paris-Saclay, Centre National de la Recherche
Scientifique, Universite Paris Sud, Universite Paris Diderot, Institut National
de la Recherche Agronomique, Universite d'Evry, Universite Paris-Saclay, 91190
Gif-sur-Yvette, France florian.frugier@cnrs.fr.
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20190219
PL - United States
TA - Plant Physiol
JT - Plant physiology
JID - 0401224
RN - 0 (Plant Proteins)
SB - IM
MH - Medicago truncatula/*physiology
MH - Metabolic Networks and Pathways
MH - Mutation
MH - Plant Proteins/genetics/*metabolism
MH - Plant Root Nodulation/*physiology
MH - Plant Roots/physiology
MH - Symbiosis
PMC - PMC6501087
EDAT- 2019/02/21 06:00
MHDA- 2020/02/27 06:00
CRDT- 2019/02/21 06:00
PHST- 2019/01/03 00:00 [received]
PHST- 2019/02/06 00:00 [accepted]
PHST- 2019/02/21 06:00 [pubmed]
PHST- 2020/02/27 06:00 [medline]
PHST- 2019/02/21 06:00 [entrez]
AID - pp.18.01588 [pii]
AID - 201801588DR1 [pii]
AID - 10.1104/pp.18.01588 [doi]
PST - ppublish
SO - Plant Physiol. 2019 May;180(1):559-570. doi: 10.1104/pp.18.01588. Epub 2019 Feb
19.
##### PUB RECORD #####
## 10.3389/fpls.2016.00034 26858743 PMC4732000 Qiao, Pingault, et al., 2016 "Qiao Z, Pingault L, Nourbakhsh-Rey M, Libault M. Comprehensive Comparative Genomic and Transcriptomic Analyses of the Legume Genes Controlling the Nodulation Process. Front Plant Sci. 2016 Jan 29;7:34. doi: 10.3389/fpls.2016.00034. PMID: 26858743; PMCID: PMC4732000." ##
PMID- 26858743
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160209
LR - 20200930
IS - 1664-462X (Print)
IS - 1664-462X (Electronic)
IS - 1664-462X (Linking)
VI - 7
DP - 2016
TI - Comprehensive Comparative Genomic and Transcriptomic Analyses of the Legume Genes
Controlling the Nodulation Process.
PG - 34
LID - 10.3389/fpls.2016.00034 [doi]
LID - 34
AB - Nitrogen is one of the most essential plant nutrients and one of the major
factors limiting crop productivity. Having the goal to perform a more sustainable
agriculture, there is a need to maximize biological nitrogen fixation, a feature
of legumes. To enhance our understanding of the molecular mechanisms controlling
the interaction between legumes and rhizobia, the symbiotic partner fixing and
assimilating the atmospheric nitrogen for the plant, researchers took advantage
of genetic and genomic resources developed across different legume models (e.g.,
Medicago truncatula, Lotus japonicus, Glycine max, and Phaseolus vulgaris) to
identify key regulatory protein coding genes of the nodulation process. In this
study, we are presenting the results of a comprehensive comparative genomic
analysis to highlight orthologous and paralogous relationships between the legume
genes controlling nodulation. Mining large transcriptomic datasets, we also
identified several orthologous and paralogous genes characterized by the
induction of their expression during nodulation across legume plant species. This
comprehensive study prompts new insights into the evolution of the nodulation
process in legume plant and will benefit the scientific community interested in
the transfer of functional genomic information between species.
FAU - Qiao, Zhenzhen
AU - Qiao Z
AD - Department of Microbiology and Plant Biology, University of Oklahoma Norman, OK,
USA.
FAU - Pingault, Lise
AU - Pingault L
AD - Department of Microbiology and Plant Biology, University of Oklahoma Norman, OK,
USA.
FAU - Nourbakhsh-Rey, Mehrnoush
AU - Nourbakhsh-Rey M
AD - Department of Microbiology and Plant Biology, University of Oklahoma Norman, OK,
USA.
FAU - Libault, Marc
AU - Libault M
AD - Department of Microbiology and Plant Biology, University of Oklahoma Norman, OK,
USA.
LA - eng
PT - Journal Article
DEP - 20160129
PL - Switzerland
TA - Front Plant Sci
JT - Frontiers in plant science
JID - 101568200
PMC - PMC4732000
OTO - NOTNLM
OT - comparative genomic
OT - comparative transcriptomic
OT - legume
OT - neo-/sub-functionalization
OT - nodulation
OT - orthologs
OT - paralogs
OT - root hair cell
EDAT- 2016/02/10 06:00
MHDA- 2016/02/10 06:01
CRDT- 2016/02/10 06:00
PHST- 2015/10/28 00:00 [received]
PHST- 2016/01/10 00:00 [accepted]
PHST- 2016/02/10 06:00 [entrez]
PHST- 2016/02/10 06:00 [pubmed]
PHST- 2016/02/10 06:01 [medline]
AID - 10.3389/fpls.2016.00034 [doi]
PST - epublish
SO - Front Plant Sci. 2016 Jan 29;7:34. doi: 10.3389/fpls.2016.00034. eCollection
2016.
##### PUB RECORD #####
## 10.1186/s12870-020-02619-6 32867687 null Jiao, Wang, et al., 2020 "Jiao Z, Wang L, Du H, Wang Y, Wang W, Liu J, Huang J, Huang W, Ge L. Genome-wide study of C2H2 zinc finger gene family in Medicago truncatula. BMC Plant Biol. 2020 Aug 31;20(1):401. doi: 10.1186/s12870-020-02619-6. PMID: 32867687; PMCID: PMC7460785." ##
PMID- 32867687
OWN - NLM
STAT- MEDLINE
DCOM- 20210218
LR - 20210218
IS - 1471-2229 (Electronic)
IS - 1471-2229 (Linking)
VI - 20
IP - 1
DP - 2020 Aug 31
TI - Genome-wide study of C2H2 zinc finger gene family in Medicago truncatula.
PG - 401
LID - 10.1186/s12870-020-02619-6 [doi]
LID - 401
AB - BACKGROUND: C2H2 zinc finger proteins (C2H2 ZFPs) play vital roles in shaping
many aspects of plant growth and adaptation to the environment. Plant genomes
harbor hundreds of C2H2 ZFPs, which compose one of the most important and largest
transcription factor families in higher plants. Although the C2H2 ZFP gene family
has been reported in several plant species, it has not been described in the
model leguminous species Medicago truncatula. RESULTS: In this study, we
identified 218 C2H2 type ZFPs with 337 individual C2H2 motifs in M. truncatula.
We showed that the high rate of local gene duplication has significantly
contributed to the expansion of the C2H2 gene family in M. truncatula. The
identified ZFPs exhibit high variation in motif arrangement and expression
pattern, suggesting that the short C2H2 zinc finger motif has been adopted as a
scaffold by numerous transcription factors with different functions to recognize
cis-elements. By analyzing the public expression datasets and quantitative RT-PCR
(qRT-PCR), we identified several C2H2 ZFPs that are specifically expressed in
certain tissues, such as the nodule, seed, and flower. CONCLUSION: Our
genome-wide work revealed an expanded C2H2 ZFP gene family in an important legume
M. truncatula, and provides new insights into the diversification and expansion
of C2H2 ZFPs in higher plants.
FAU - Jiao, Zhicheng
AU - Jiao Z
AD - Department of Grassland Science, College of Forestry and Landscape Architecture,
South China Agricultural University, Guangzhou, 510642, Guangdong, China.
AD - Guangdong Engineering Research Center for Grassland Science, Tianhe, 483 Wushan
Road, Guangzhou, 510642, Guangdong, China.
AD - Guangdong Key Laboratory for Innovative Development and Utilization of Forest
Plant Germplasm, South China Agricultural University, Guangzhou, 510642,
Guangdong, China.
FAU - Wang, Liping
AU - Wang L
AD - State Key Laboratory for Conservation and Utilization of Subtropical
Agro-Bioresources, South China Agricultural University, Guangzhou, 510642,
Guangdong, China.
AD - College of Life Sciences, South China Agricultural University, Guangzhou, 510642,
Guangdong, China.
FAU - Du, Huan
AU - Du H
AD - Department of Grassland Science, College of Forestry and Landscape Architecture,
South China Agricultural University, Guangzhou, 510642, Guangdong, China.
AD - Guangdong Engineering Research Center for Grassland Science, Tianhe, 483 Wushan
Road, Guangzhou, 510642, Guangdong, China.
AD - Guangdong Key Laboratory for Innovative Development and Utilization of Forest
Plant Germplasm, South China Agricultural University, Guangzhou, 510642,
Guangdong, China.
FAU - Wang, Ying
AU - Wang Y
AD - Department of Grassland Science, College of Forestry and Landscape Architecture,
South China Agricultural University, Guangzhou, 510642, Guangdong, China.
AD - Guangdong Engineering Research Center for Grassland Science, Tianhe, 483 Wushan
Road, Guangzhou, 510642, Guangdong, China.
AD - Guangdong Key Laboratory for Innovative Development and Utilization of Forest
Plant Germplasm, South China Agricultural University, Guangzhou, 510642,
Guangdong, China.
FAU - Wang, Weixu
AU - Wang W
AD - Department of Grassland Science, College of Forestry and Landscape Architecture,
South China Agricultural University, Guangzhou, 510642, Guangdong, China.
AD - Guangdong Engineering Research Center for Grassland Science, Tianhe, 483 Wushan
Road, Guangzhou, 510642, Guangdong, China.
FAU - Liu, Junjie
AU - Liu J
AD - Department of Grassland Science, College of Forestry and Landscape Architecture,
South China Agricultural University, Guangzhou, 510642, Guangdong, China.
AD - Guangdong Engineering Research Center for Grassland Science, Tianhe, 483 Wushan
Road, Guangzhou, 510642, Guangdong, China.
FAU - Huang, Jinhang
AU - Huang J
AD - Department of Grassland Science, College of Forestry and Landscape Architecture,
South China Agricultural University, Guangzhou, 510642, Guangdong, China.
AD - Guangdong Engineering Research Center for Grassland Science, Tianhe, 483 Wushan
Road, Guangzhou, 510642, Guangdong, China.
FAU - Huang, Wei
AU - Huang W
AD - State Key Laboratory for Conservation and Utilization of Subtropical
Agro-Bioresources, South China Agricultural University, Guangzhou, 510642,
Guangdong, China.
AD - College of Life Sciences, South China Agricultural University, Guangzhou, 510642,
Guangdong, China.
FAU - Ge, Liangfa
AU - Ge L
AUID- ORCID: 0000-0002-4831-4637
AD - Department of Grassland Science, College of Forestry and Landscape Architecture,
South China Agricultural University, Guangzhou, 510642, Guangdong, China.
lge@scau.edu.cn.
AD - Guangdong Engineering Research Center for Grassland Science, Tianhe, 483 Wushan
Road, Guangzhou, 510642, Guangdong, China. lge@scau.edu.cn.
AD - Guangdong Key Laboratory for Innovative Development and Utilization of Forest
Plant Germplasm, South China Agricultural University, Guangzhou, 510642,
Guangdong, China. lge@scau.edu.cn.
LA - eng
PT - Journal Article
DEP - 20200831
PL - England
TA - BMC Plant Biol
JT - BMC plant biology
JID - 100967807
SB - IM
MH - CYS2-HIS2 Zinc Fingers/*genetics
MH - *Gene Duplication
MH - Genes, Plant/*genetics
MH - *Genome-Wide Association Study
MH - Medicago truncatula/*genetics
MH - *Multigene Family
PMC - PMC7460785
OTO - NOTNLM
OT - C2H2
OT - EAR motif
OT - Expression
OT - Gene family
OT - Local gene duplication
OT - Zinc finger
COIS- The authors declare that they have no competing interests.
EDAT- 2020/09/02 06:00
MHDA- 2021/02/20 06:00
CRDT- 2020/09/02 06:00
PHST- 2019/07/24 00:00 [received]
PHST- 2020/08/25 00:00 [accepted]
PHST- 2020/09/02 06:00 [entrez]
PHST- 2020/09/02 06:00 [pubmed]
PHST- 2021/02/20 06:00 [medline]
AID - 10.1186/s12870-020-02619-6 [pii]
AID - 2619 [pii]
AID - 10.1186/s12870-020-02619-6 [doi]
PST - epublish
SO - BMC Plant Biol. 2020 Aug 31;20(1):401. doi: 10.1186/s12870-020-02619-6.
##### PUB RECORD #####
## 10.1038/s41477-018-0286-7 30397259 null Pecrix, Staton, et al., 2018 "Pecrix Y, Staton SE, Sallet E, Lelandais-Brière C, Moreau S, Carrère S, Blein T, Jardinaud MF, Latrasse D, Zouine M, Zahm M, Kreplak J, Mayjonade B, Satgé C, Perez M, Cauet S, Marande W, Chantry-Darmon C, Lopez-Roques C, Bouchez O, Bérard A, Debellé F, Muños S, Bendahmane A, Bergès H, Niebel A, Buitink J, Frugier F, Benhamed M, Crespi M, Gouzy J, Gamas P. Whole-genome landscape of Medicago truncatula symbiotic genes. Nat Plants. 2018 Dec;4(12):1017-1025. doi: 10.1038/s41477-018-0286-7. Epub 2018 Nov 5. PMID: 30397259." ##
PMID- 30397259
OWN - NLM
STAT- MEDLINE
DCOM- 20190701
LR - 20191029
IS - 2055-0278 (Electronic)
IS - 2055-0278 (Linking)
VI - 4
IP - 12
DP - 2018 Dec
TI - Whole-genome landscape of Medicago truncatula symbiotic genes.
PG - 1017-1025
LID - 10.1038/s41477-018-0286-7 [doi]
AB - Advances in deciphering the functional architecture of eukaryotic genomes have
been facilitated by recent breakthroughs in sequencing technologies, enabling a
more comprehensive representation of genes and repeat elements in genome sequence
assemblies, as well as more sensitive and tissue-specific analyses of gene
expression. Here we show that PacBio sequencing has led to a substantially
improved genome assembly of Medicago truncatula A17, a legume model species
notable for endosymbiosis studies(1), and has enabled the identification of
genome rearrangements between genotypes at a near-base-pair resolution.
Annotation of the new M. truncatula genome sequence has allowed for a thorough
analysis of transposable elements and their dynamics, as well as the
identification of new players involved in symbiotic nodule development, in
particular 1,037 upregulated long non-coding RNAs (lncRNAs). We have also
discovered that a substantial proportion (~35% and 38%, respectively) of the
genes upregulated in nodules or expressed in the nodule differentiation zone
colocalize in genomic clusters (270 and 211, respectively), here termed symbiotic
islands. These islands contain numerous expressed lncRNA genes and display
differentially both DNA methylation and histone marks. Epigenetic regulations and
lncRNAs are therefore attractive candidate elements for the orchestration of
symbiotic gene expression in the M. truncatula genome.
FAU - Pecrix, Yann
AU - Pecrix Y
AUID- ORCID: 0000-0002-6537-3145
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Staton, S Evan
AU - Staton SE
AUID- ORCID: 0000-0002-5681-6047
AD - University of British Columbia, Vancouver, Canada.
FAU - Sallet, Erika
AU - Sallet E
AUID- ORCID: 0000-0003-4637-473X
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Lelandais-Briere, Christine
AU - Lelandais-Briere C
AD - IPS2, CNRS, INRA, Universities of Paris Diderot and Sorbonne Paris Cite, Gif sur
Yvette, France.
AD - IPS2, CNRS, INRA, Universities of Paris Diderot, Paris Sud, Evry and
Paris-Saclay, Gif sur Yvette, France.
FAU - Moreau, Sandra
AU - Moreau S
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Carrere, Sebastien
AU - Carrere S
AUID- ORCID: 0000-0002-2348-0778
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Blein, Thomas
AU - Blein T
AD - IPS2, CNRS, INRA, Universities of Paris Diderot and Sorbonne Paris Cite, Gif sur
Yvette, France.
AD - IPS2, CNRS, INRA, Universities of Paris Diderot, Paris Sud, Evry and
Paris-Saclay, Gif sur Yvette, France.
FAU - Jardinaud, Marie-Francoise
AU - Jardinaud MF
AD - LIPM, Universite de Toulouse, INPT, ENSAT, Castanet-Tolosan, France.
FAU - Latrasse, David
AU - Latrasse D
AD - IPS2, CNRS, INRA, Universities of Paris Diderot and Sorbonne Paris Cite, Gif sur
Yvette, France.
AD - IPS2, CNRS, INRA, Universities of Paris Diderot, Paris Sud, Evry and
Paris-Saclay, Gif sur Yvette, France.
FAU - Zouine, Mohamed
AU - Zouine M
AD - GBF, Universite de Toulouse, INPT, ENSAT, Castanet-Tolosan, France.
FAU - Zahm, Margot
AU - Zahm M
AD - GBF, Universite de Toulouse, INPT, ENSAT, Castanet-Tolosan, France.
FAU - Kreplak, Jonathan
AU - Kreplak J
AD - AGROECOLOGIE, INRA, Dijon, France.
FAU - Mayjonade, Baptiste
AU - Mayjonade B
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Satge, Carine
AU - Satge C
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
AD - CNRGV, INRA, Castanet-Tolosan, France.
FAU - Perez, Magali
AU - Perez M
AD - IPS2, CNRS, INRA, Universities of Paris Diderot and Sorbonne Paris Cite, Gif sur
Yvette, France.
AD - IPS2, CNRS, INRA, Universities of Paris Diderot, Paris Sud, Evry and
Paris-Saclay, Gif sur Yvette, France.
FAU - Cauet, Stephane
AU - Cauet S
AD - CNRGV, INRA, Castanet-Tolosan, France.
FAU - Marande, William
AU - Marande W
AD - CNRGV, INRA, Castanet-Tolosan, France.
FAU - Chantry-Darmon, Celine
AU - Chantry-Darmon C
AD - CNRGV, INRA, Castanet-Tolosan, France.
FAU - Lopez-Roques, Celine
AU - Lopez-Roques C
AD - INRA, US1426, GeT-PlaGe, Genotoul, Castanet-Tolosan, France.
FAU - Bouchez, Olivier
AU - Bouchez O
AD - INRA, US1426, GeT-PlaGe, Genotoul, Castanet-Tolosan, France.
FAU - Berard, Aurelie
AU - Berard A
AD - INRA, US 1279 EPGV, Universite Paris-Saclay, Evry, France.
FAU - Debelle, Frederic
AU - Debelle F
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Munos, Stephane
AU - Munos S
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Bendahmane, Abdelhafid
AU - Bendahmane A
AD - IPS2, CNRS, INRA, Universities of Paris Diderot and Sorbonne Paris Cite, Gif sur
Yvette, France.
AD - IPS2, CNRS, INRA, Universities of Paris Diderot, Paris Sud, Evry and
Paris-Saclay, Gif sur Yvette, France.
FAU - Berges, Helene
AU - Berges H
AD - CNRGV, INRA, Castanet-Tolosan, France.
FAU - Niebel, Andreas
AU - Niebel A
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
FAU - Buitink, Julia
AU - Buitink J
AUID- ORCID: 0000-0002-1457-764X
AD - IRHS, Agrocampus-Ouest, INRA, Universite d'Angers, Beaucouze, France.
FAU - Frugier, Florian
AU - Frugier F
AD - IPS2, CNRS, INRA, Universities of Paris Diderot and Sorbonne Paris Cite, Gif sur
Yvette, France.
AD - IPS2, CNRS, INRA, Universities of Paris Diderot, Paris Sud, Evry and
Paris-Saclay, Gif sur Yvette, France.
FAU - Benhamed, Moussa
AU - Benhamed M
AD - IPS2, CNRS, INRA, Universities of Paris Diderot and Sorbonne Paris Cite, Gif sur
Yvette, France.
AD - IPS2, CNRS, INRA, Universities of Paris Diderot, Paris Sud, Evry and
Paris-Saclay, Gif sur Yvette, France.
FAU - Crespi, Martin
AU - Crespi M
AD - IPS2, CNRS, INRA, Universities of Paris Diderot and Sorbonne Paris Cite, Gif sur
Yvette, France.
AD - IPS2, CNRS, INRA, Universities of Paris Diderot, Paris Sud, Evry and
Paris-Saclay, Gif sur Yvette, France.
FAU - Gouzy, Jerome
AU - Gouzy J
AUID- ORCID: 0000-0001-5695-4557
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
Jerome.Gouzy@inra.fr.
FAU - Gamas, Pascal
AU - Gamas P
AUID- ORCID: 0000-0002-6253-4249
AD - LIPM, Universite de Toulouse, INRA, CNRS, Castanet-Tolosan, France.
Pascal.Gamas@inra.fr.
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20181105
PL - England
TA - Nat Plants
JT - Nature plants
JID - 101651677
RN - 0 (Plant Proteins)
RN - 0 (RNA, Plant)
RN - 0 (RNA, Untranslated)
SB - IM
MH - DNA Methylation
MH - *Epigenesis, Genetic
MH - Gene Expression Regulation, Plant
MH - Genome, Plant/*genetics
MH - Genomics
MH - Medicago truncatula/*genetics
MH - Multigene Family
MH - Plant Proteins/genetics
MH - RNA, Plant/genetics
MH - RNA, Untranslated/*genetics
MH - Root Nodules, Plant/genetics
MH - Symbiosis/*genetics
EDAT- 2018/11/07 06:00
MHDA- 2019/07/02 06:00
CRDT- 2018/11/07 06:00
PHST- 2018/03/07 00:00 [received]
PHST- 2018/09/21 00:00 [accepted]
PHST- 2018/11/07 06:00 [pubmed]
PHST- 2019/07/02 06:00 [medline]
PHST- 2018/11/07 06:00 [entrez]
AID - 10.1038/s41477-018-0286-7 [pii]
AID - 10.1038/s41477-018-0286-7 [doi]
PST - ppublish
SO - Nat Plants. 2018 Dec;4(12):1017-1025. doi: 10.1038/s41477-018-0286-7. Epub 2018
Nov 5.
##### PUB RECORD #####
## 10.1093/plphys/kiaa005 33631796 PMC8133602 Cheng, Li, et al., 2021 "Cheng X, Li G, Krom N, Tang Y, Wen J. Genetic regulation of flowering time and inflorescence architecture by MtFDa and MtFTa1 in Medicago truncatula. Plant Physiol. 2021 Feb 25;185(1):161-178. doi: 10.1093/plphys/kiaa005. PMID: 33631796; PMCID: PMC8133602." ##
PMID- 33631796
OWN - NLM
STAT- MEDLINE
DCOM- 20210705
LR - 20211120
IS - 1532-2548 (Electronic)
IS - 0032-0889 (Print)
IS - 0032-0889 (Linking)
VI - 185
IP - 1
DP - 2021 Feb 25
TI - Genetic regulation of flowering time and inflorescence architecture by MtFDa and
MtFTa1 in Medicago truncatula.
PG - 161-178
LID - 10.1093/plphys/kiaa005 [doi]
AB - Regulation of floral transition and inflorescence development is crucial for
plant reproductive success. FLOWERING LOCUS T (FT) is one of the central players
in the flowering genetic regulatory network, whereas FLOWERING LOCUS D (FD), an
interactor of FT and TERMINAL FLOWER 1 (TFL1), plays significant roles in both
floral transition and inflorescence development. Here we show the genetic
regulatory networks of floral transition and inflorescence development in
Medicago truncatula by characterizing MtFTa1 and MtFDa and their genetic
interactions with key inflorescence meristem (IM) regulators. Both MtFTa1 and
MtFDa promote flowering; the double mutant mtfda mtfta1 does not proceed to
floral transition. RNAseq analysis reveals that a broad range of genes involved
in flowering regulation and flower development are up- or downregulated by MtFTa1
and/or MtFDa mutations. Furthermore, mutation of MtFDa also affects the
inflorescence architecture. Genetic analyses of MtFDa, MtFTa1, MtTFL1, and MtFULc
show that MtFDa is epistatic to MtFULc and MtTFL1 in controlling IM identity. Our
results demonstrate that MtFTa1 and MtFDa are major flowering regulators in M.
truncatula, and MtFDa is essential both in floral transition and secondary
inflorescence development. The study will advance our understanding of the
genetic regulation of flowering time and inflorescence development in legumes.
CI - (c) The Author(s) 2020. Published by Oxford University Press on behalf of American
Society of Plant Biologists.
FAU - Cheng, Xiaofei
AU - Cheng X
AD - Noble Research Institute, Ardmore, Oklahoma 73401, USA.
FAU - Li, Guifen
AU - Li G
AD - Noble Research Institute, Ardmore, Oklahoma 73401, USA.
FAU - Krom, Nick
AU - Krom N
AD - Noble Research Institute, Ardmore, Oklahoma 73401, USA.
FAU - Tang, Yuhong
AU - Tang Y
AD - Noble Research Institute, Ardmore, Oklahoma 73401, USA.
FAU - Wen, Jiangqi
AU - Wen J
AD - Noble Research Institute, Ardmore, Oklahoma 73401, USA.
LA - eng
PT - Comparative Study
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
PL - United States
TA - Plant Physiol
JT - Plant physiology
JID - 0401224
SB - IM
MH - Gene Expression Regulation, Developmental
MH - Gene Expression Regulation, Plant
MH - Gene Regulatory Networks
MH - Genes, Plant
MH - Genetic Variation
MH - Genotype
MH - Inflorescence/*anatomy & histology/*genetics/*growth & development
MH - Magnoliopsida/*genetics/*growth & development
MH - Medicago truncatula/*genetics/*growth & development
MH - Mutation
MH - Phenotype
MH - Plants, Genetically Modified
PMC - PMC8133602
EDAT- 2021/02/26 06:00
MHDA- 2021/07/06 06:00
CRDT- 2021/02/25 20:19
PHST- 2020/08/03 00:00 [received]
PHST- 2020/10/11 00:00 [accepted]
PHST- 2021/02/25 20:19 [entrez]
PHST- 2021/02/26 06:00 [pubmed]
PHST- 2021/07/06 06:00 [medline]
AID - 5985539 [pii]
AID - kiaa005 [pii]
AID - 10.1093/plphys/kiaa005 [doi]
PST - ppublish
SO - Plant Physiol. 2021 Feb 25;185(1):161-178. doi: 10.1093/plphys/kiaa005.
##### PUB RECORD #####
## 10.1105/tpc.111.089128 22080596 PMC3246329 Peng, Yu, et al., 2011 "Peng J, Yu J, Wang H, Guo Y, Li G, Bai G, Chen R. Regulation of compound leaf development in Medicago truncatula by fused compound leaf1, a class M KNOX gene. Plant Cell. 2011 Nov;23(11):3929-43. doi: 10.1105/tpc.111.089128. Epub 2011 Nov 11. PMID: 22080596; PMCID: PMC3246329." ##
PMID- 22080596
OWN - NLM
STAT- MEDLINE
DCOM- 20120821
LR - 20220408
IS - 1532-298X (Electronic)
IS - 1040-4651 (Print)
IS - 1040-4651 (Linking)
VI - 23
IP - 11
DP - 2011 Nov
TI - Regulation of compound leaf development in Medicago truncatula by fused compound
leaf1, a class M KNOX gene.
PG - 3929-43
LID - 10.1105/tpc.111.089128 [doi]
AB - Medicago truncatula is a legume species belonging to the inverted repeat lacking
clade (IRLC) with trifoliolate compound leaves. However, the regulatory
mechanisms underlying development of trifoliolate leaves in legumes remain
largely unknown. Here, we report isolation and characterization of fused compound
leaf1 (fcl1) mutants of M. truncatula. Phenotypic analysis suggests that FCL1
plays a positive role in boundary separation and proximal-distal axis development
of compound leaves. Map-based cloning indicates that FCL1 encodes a class M KNOX
protein that harbors the MEINOX domain but lacks the homeodomain. Yeast
two-hybrid assays show that FCL1 interacts with a subset of Arabidopsis thaliana
BEL1-like proteins with slightly different substrate specificities from the
Arabidopsis homolog KNATM-B. Double mutant analyses with M. truncatula single
leaflet1 (sgl1) and palmate-like pentafoliata1 (palm1) leaf mutants show that
fcl1 is epistatic to palm1 and sgl1 is epistatic to fcl1 in terms of leaf
complexity and that SGL1 and FCL1 act additively and are required for petiole
development. Previous studies have shown that the canonical KNOX proteins are not
involved in compound leaf development in IRLC legumes. The identification of FCL1
supports the role of a truncated KNOX protein in compound leaf development in M.
truncatula.
FAU - Peng, Jianling
AU - Peng J
AD - Plant Biology Division, The Samuel Roberts Noble Foundation, Ardmore, Oklahoma
73401, USA.
FAU - Yu, Jianbin
AU - Yu J
FAU - Wang, Hongliang
AU - Wang H
FAU - Guo, Yingqing
AU - Guo Y
FAU - Li, Guangming
AU - Li G
FAU - Bai, Guihua
AU - Bai G
FAU - Chen, Rujin
AU - Chen R
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
PT - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20111111
PL - England
TA - Plant Cell
JT - The Plant cell
JID - 9208688
RN - 0 (Arabidopsis Proteins)
RN - 0 (BEL1 protein, Arabidopsis)
RN - 0 (Homeodomain Proteins)
RN - 0 (Plant Proteins)
RN - 0 (Transcription Factors)
SB - IM
MH - Arabidopsis Proteins/genetics
MH - Cloning, Molecular
MH - Epistasis, Genetic
MH - Gene Expression Regulation, Plant
MH - Genes, Plant
MH - Homeodomain Proteins/genetics
MH - Medicago truncatula/*genetics/*growth & development
MH - Mutation
MH - Plant Leaves/genetics/*growth & development
MH - Plant Proteins/*genetics/*metabolism
MH - Sequence Homology, Nucleic Acid
MH - Transcription Factors/genetics
MH - Two-Hybrid System Techniques
PMC - PMC3246329
EDAT- 2011/11/15 06:00
MHDA- 2012/08/22 06:00
CRDT- 2011/11/15 06:00
PHST- 2011/11/15 06:00 [entrez]
PHST- 2011/11/15 06:00 [pubmed]
PHST- 2012/08/22 06:00 [medline]
AID - tpc.111.089128 [pii]
AID - 089128 [pii]
AID - 10.1105/tpc.111.089128 [doi]
PST - ppublish
SO - Plant Cell. 2011 Nov;23(11):3929-43. doi: 10.1105/tpc.111.089128. Epub 2011 Nov
11.
##### PUB RECORD #####
## 10.1104/pp.15.00164 25792252 null Weller, Foo, et al., 2015 "Weller JL, Foo EM, Hecht V, Ridge S, Vander Schoor JK, Reid JB. Ethylene Signaling Influences Light-Regulated Development in Pea. Plant Physiol. 2015 Sep;169(1):115-24. doi: 10.1104/pp.15.00164. Epub 2015 Mar 19. PMID: 25792252; PMCID: PMC4577373." ##
PMID- 25792252
OWN - NLM
STAT- MEDLINE
DCOM- 20160707
LR - 20220310
IS - 1532-2548 (Electronic)
IS - 0032-0889 (Print)
IS - 0032-0889 (Linking)
VI - 169
IP - 1
DP - 2015 Sep
TI - Ethylene Signaling Influences Light-Regulated Development in Pea.
PG - 115-24
LID - 10.1104/pp.15.00164 [doi]
AB - Plant responses to light involve a complex network of interactions among multiple
plant hormones. In a screen for mutants showing altered photomorphogenesis under
red light, we identified a mutant with dramatically enhanced leaf expansion and
delayed petal senescence. We show that this mutant exhibits reduced sensitivity
to ethylene and carries a nonsense mutation in the single pea (Pisum sativum)
ortholog of the ethylene signaling gene ETHYLENE INSENSITIVE2 (EIN2). Consistent
with this observation, the ein2 mutation rescues the previously described effects
of ethylene overproduction in mature phytochrome-deficient plants. In seedlings,
ein2 confers a marked increase in leaf expansion under monochromatic red,
far-red, or blue light, and interaction with phytochromeA, phytochromeB, and
long1 mutants confirms that ein2 enhances both phytochrome- and
cryptochrome-dependent responses in a LONG1-dependent manner. In contrast,
minimal effects of ein2 on seedling development in darkness or high-irradiance
white light show that ethylene is not limiting for development under these
conditions. These results indicate that ethylene signaling constrains leaf
expansion during deetiolation in pea and provide further evidence that
down-regulation of ethylene production may be an important component mechanism in
the broader control of photomorphogenic development by phytochrome and
cryptochrome.
CI - (c) 2015 American Society of Plant Biologists. All Rights Reserved.
FAU - Weller, James L
AU - Weller JL
AUID- ORCID: 0000-0003-2423-8286
AD - School of Biological Sciences, University of Tasmania, Hobart, Tasmania 7001,
Australia jim.weller@utas.edu.au.
FAU - Foo, Eloise M
AU - Foo EM
AUID- ORCID: 0000-0002-9751-8433
AD - School of Biological Sciences, University of Tasmania, Hobart, Tasmania 7001,
Australia.
FAU - Hecht, Valerie
AU - Hecht V
AUID- ORCID: 0000-0002-3539-3356
AD - School of Biological Sciences, University of Tasmania, Hobart, Tasmania 7001,
Australia.
FAU - Ridge, Stephen
AU - Ridge S
AD - School of Biological Sciences, University of Tasmania, Hobart, Tasmania 7001,
Australia.
FAU - Vander Schoor, Jacqueline K
AU - Vander Schoor JK
AD - School of Biological Sciences, University of Tasmania, Hobart, Tasmania 7001,
Australia.
FAU - Reid, James B
AU - Reid JB
AD - School of Biological Sciences, University of Tasmania, Hobart, Tasmania 7001,
Australia.
LA - eng
SI - GENBANK/KP202149
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20150319
PL - United States
TA - Plant Physiol
JT - Plant physiology
JID - 0401224
RN - 0 (Cryptochromes)
RN - 0 (Ethylenes)
RN - 0 (Plant Growth Regulators)
RN - 0 (Plant Proteins)
RN - 11121-56-5 (Phytochrome)
RN - 91GW059KN7 (ethylene)
SB - IM
MH - Cryptochromes/metabolism
MH - Darkness
MH - Down-Regulation
MH - Ethylenes/*metabolism
MH - Gene Expression Regulation, Developmental
MH - Gene Expression Regulation, Plant
MH - Light
MH - Molecular Sequence Data
MH - Mutation
MH - Peas/genetics/growth & development/*physiology/radiation effects
MH - Phytochrome/*metabolism
MH - Plant Growth Regulators/*metabolism
MH - Plant Leaves/genetics/growth & development/physiology/radiation effects
MH - Plant Proteins/genetics/*metabolism
MH - Seedlings/genetics/growth & development/physiology/radiation effects
MH - Signal Transduction
PMC - PMC4577373
EDAT- 2015/03/21 06:00
MHDA- 2016/07/09 06:00
CRDT- 2015/03/21 06:00
PHST- 2015/02/02 00:00 [received]
PHST- 2015/03/17 00:00 [accepted]
PHST- 2015/03/21 06:00 [entrez]
PHST- 2015/03/21 06:00 [pubmed]
PHST- 2016/07/09 06:00 [medline]
AID - pp.15.00164 [pii]
AID - PP201500164 [pii]
AID - 10.1104/pp.15.00164 [doi]
PST - ppublish
SO - Plant Physiol. 2015 Sep;169(1):115-24. doi: 10.1104/pp.15.00164. Epub 2015 Mar
19.
##### PUB RECORD #####
## 10.1105/tpc.19.00609 32303662 PMC7268793 Ribeiro, Lacchini, et al., 2020 "Ribeiro B, Lacchini E, Bicalho KU, Mertens J, Arendt P, Vanden Bossche R, Calegario G, Gryffroy L, Ceulemans E, Buitink J, Goossens A, Pollier J. A Seed-Specific Regulator of Triterpene Saponin Biosynthesis in Medicago truncatula. Plant Cell. 2020 Jun;32(6):2020-2042. doi: 10.1105/tpc.19.00609. Epub 2020 Apr 17. PMID: 32303662; PMCID: PMC7268793." ##
PMID- 32303662
OWN - NLM
STAT- MEDLINE
DCOM- 20210204
LR - 20210602
IS - 1532-298X (Electronic)
IS - 1040-4651 (Print)
IS - 1040-4651 (Linking)
VI - 32
IP - 6
DP - 2020 Jun
TI - A Seed-Specific Regulator of Triterpene Saponin Biosynthesis in Medicago
truncatula.
PG - 2020-2042
LID - 10.1105/tpc.19.00609 [doi]
AB - Plants produce a vast array of defense compounds to protect themselves from
pathogen attack or herbivore predation. Saponins are a specific class of defense
compounds comprising bioactive glycosides with a steroidal or triterpenoid
aglycone backbone. The model legume Medicago truncatula synthesizes two types of
saponins, hemolytic saponins and nonhemolytic soyasaponins, which accumulate as
specific blends in different plant organs. Here, we report the identification of
the seed-specific transcription factor TRITERPENE SAPONIN ACTIVATION REGULATOR3
(TSAR3), which controls hemolytic saponin biosynthesis in developing M.
truncatula seeds. Analysis of genes that are coexpressed with TSAR3 in
transcriptome data sets from developing M. truncatula seeds led to the
identification of CYP88A13, a cytochrome P450 that catalyzes the C-16alpha
hydroxylation of medicagenic acid toward zanhic acid, the final oxidation step of
the hemolytic saponin biosynthesis branch in M. truncatula In addition, two
uridine diphosphate glycosyltransferases, UGT73F18 and UGT73F19, which
glucosylate hemolytic sapogenins at the C-3 position, were identified. The genes
encoding the identified biosynthetic enzymes are present in clusters of
duplicated genes in the M. truncatula genome. This appears to be a common theme
among saponin biosynthesis genes, especially glycosyltransferases, and may be the
driving force of the metabolic evolution of saponins.
CI - (c) 2020 American Society of Plant Biologists. All rights reserved.
FAU - Ribeiro, Bianca
AU - Ribeiro B
AUID- ORCID: 0000-0002-1843-0258
AD - Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052
Ghent, Belgium.
AD - VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
FAU - Lacchini, Elia
AU - Lacchini E
AUID- ORCID: 0000-0002-1598-8950
AD - Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052
Ghent, Belgium.
AD - VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
FAU - Bicalho, Keylla U
AU - Bicalho KU
AUID- ORCID: 0000-0002-5165-9070
AD - Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052
Ghent, Belgium.
AD - VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
AD - Department of Organic Chemistry, Institute of Chemistry, Sao Paulo State
University (UNESP), Araraquara, Sao Paulo 14800-900, Brazil.
FAU - Mertens, Jan
AU - Mertens J
AUID- ORCID: 0000-0002-8095-0748
AD - Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052
Ghent, Belgium.
AD - VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
FAU - Arendt, Philipp
AU - Arendt P
AUID- ORCID: 0000-0001-7429-0803
AD - Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052
Ghent, Belgium.
AD - VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
FAU - Vanden Bossche, Robin
AU - Vanden Bossche R
AUID- ORCID: 0000-0001-6407-8139
AD - Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052
Ghent, Belgium.
AD - VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
FAU - Calegario, Gabriela
AU - Calegario G
AUID- ORCID: 0000-0002-3772-8447
AD - Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052
Ghent, Belgium.
AD - VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
FAU - Gryffroy, Lore
AU - Gryffroy L
AUID- ORCID: 0000-0001-9202-2992
AD - Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052
Ghent, Belgium.
AD - VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
FAU - Ceulemans, Evi
AU - Ceulemans E
AUID- ORCID: 0000-0002-3083-5768
AD - Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052
Ghent, Belgium.
AD - VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
FAU - Buitink, Julia
AU - Buitink J
AUID- ORCID: 0000-0002-1457-764X
AD - Institut de Recherche en Horticulture et Semences-Unites Mixtes de Recherche,
Universite d'Angers, INRAE, Institut Agro, SFR 4207 QuaSaV, 49071 Beaucouze,
France.
FAU - Goossens, Alain
AU - Goossens A
AUID- ORCID: 0000-0002-1599-551X
AD - Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052
Ghent, Belgium alain.goossens@psb-vib.ugent.be jacob.pollier@psb-vib.ugent.be.
AD - VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
FAU - Pollier, Jacob
AU - Pollier J
AUID- ORCID: 0000-0002-1134-9238
AD - Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052
Ghent, Belgium alain.goossens@psb-vib.ugent.be jacob.pollier@psb-vib.ugent.be.
AD - VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
AD - VIB Metabolomics Core, 9052 Ghent, Belgium.
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20200417
PL - England
TA - Plant Cell
JT - The Plant cell
JID - 9208688
RN - 0 (Plant Proteins)
RN - 0 (Triterpenes)
SB - IM
MH - Gene Expression Regulation, Plant
MH - Medicago truncatula/genetics/*metabolism
MH - Plant Proteins/genetics/*metabolism
MH - Seeds/*metabolism
MH - Triterpenes/*metabolism
PMC - PMC7268793
EDAT- 2020/04/19 06:00
MHDA- 2021/02/05 06:00
CRDT- 2020/04/19 06:00
PHST- 2019/08/07 00:00 [received]
PHST- 2020/03/27 00:00 [revised]
PHST- 2020/04/10 00:00 [accepted]
PHST- 2020/04/19 06:00 [pubmed]
PHST- 2021/02/05 06:00 [medline]
PHST- 2020/04/19 06:00 [entrez]
AID - tpc.19.00609 [pii]
AID - 201900609R2 [pii]
AID - 10.1105/tpc.19.00609 [doi]
PST - ppublish
SO - Plant Cell. 2020 Jun;32(6):2020-2042. doi: 10.1105/tpc.19.00609. Epub 2020 Apr
17.
##### PUB RECORD #####
## 10.1111/nph.13162 25406544 null Carelli, Biazzi, et al., 2014 "Carelli M, Biazzi E, Tava A, Losini I, Abbruscato P, Depedro C, Scotti C. Sapogenin content variation in Medicago inter-specific hybrid derivatives highlights some aspects of saponin synthesis and control. New Phytol. 2015 Apr;206(1):303-314. doi: 10.1111/nph.13162. Epub 2014 Nov 18. PMID: 25406544." ##
PMID- 25406544
OWN - NLM
STAT- MEDLINE
DCOM- 20160211
LR - 20201109
IS - 1469-8137 (Electronic)
IS - 0028-646X (Linking)
VI - 206
IP - 1
DP - 2015 Apr
TI - Sapogenin content variation in Medicago inter-specific hybrid derivatives
highlights some aspects of saponin synthesis and control.
PG - 303-314
LID - 10.1111/nph.13162 [doi]
AB - In the Medicago genus, saponins are a complex mixture of triterpene glycosides
showing a broad spectrum of biological properties. Here we analyzed the variation
in the sapogenin content and composition of inter-specific hybrid Medicago
sativa x Medicago arborea derivatives to highlight the pattern of this variation
in plant organs (leaves/roots) and the possible mechanisms underlying it. In
Sativa Arborea Cross (SAC) leaves and roots, saponins and sapogenins were
evaluated using chromatographic methods. Phenotypic correlations between
sapogenin content and bio-agronomic traits were examined. Expression studies on
beta-amyrin synthase and four cytochromes P450 (CYPs) involved in sapogenin
biosynthesis and sequence analysis of the key gene of the hemolytic sapogenin
pathway (CYP716A12) were performed. Chromatographic analyses revealed a different
pattern of among-family variation for hemolytic and nonhemolytic sapogenins and
saponins and for the two organs/tissues. Different correlation patterns of gene
expression in roots and leaves were found. Diachronic analysis revealed a
relationship between sapogenin content and gene transcriptional levels in the
early stages of the productive cycle. The results suggest that there are
different control mechanisms acting on sapogenin biosynthesis for leaves and
roots, which are discussed. A key role for medicagenic acid in the control of
sapogenin content in both the tissues is proposed and discussed.
CI - (c) 2014 The Authors. New Phytologist (c) 2014 New Phytologist Trust.
FAU - Carelli, Maria
AU - Carelli M
AD - Consiglio per la Ricerca e la Sperimentazione in Agricoltura, Centro di Ricerca
per le Produzioni Foraggere e Lattiero-Casearie, viale Piacenza 29, 26900, Lodi,
Italy.
FAU - Biazzi, Elisa
AU - Biazzi E
AD - Consiglio per la Ricerca e la Sperimentazione in Agricoltura, Centro di Ricerca
per le Produzioni Foraggere e Lattiero-Casearie, viale Piacenza 29, 26900, Lodi,
Italy.
FAU - Tava, Aldo
AU - Tava A
AD - Consiglio per la Ricerca e la Sperimentazione in Agricoltura, Centro di Ricerca
per le Produzioni Foraggere e Lattiero-Casearie, viale Piacenza 29, 26900, Lodi,
Italy.
FAU - Losini, Ilaria
AU - Losini I
AD - Parco Tecnologico Padano, via Einsten- Loc. Cascina Codazza, 26900, Lodi, Italy.
FAU - Abbruscato, Pamela
AU - Abbruscato P
AD - Parco Tecnologico Padano, via Einsten- Loc. Cascina Codazza, 26900, Lodi, Italy.
FAU - Depedro, Claudia
AU - Depedro C
AD - Consiglio per la Ricerca e la Sperimentazione in Agricoltura, Centro di Ricerca
per le Produzioni Foraggere e Lattiero-Casearie, viale Piacenza 29, 26900, Lodi,
Italy.
FAU - Scotti, Carla
AU - Scotti C
AD - Consiglio per la Ricerca e la Sperimentazione in Agricoltura, Centro di Ricerca
per le Produzioni Foraggere e Lattiero-Casearie, viale Piacenza 29, 26900, Lodi,
Italy.
LA - eng
SI - GENBANK/KM978958
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20141118
PL - England
TA - New Phytol
JT - The New phytologist
JID - 9882884
RN - 0 (Plant Proteins)
RN - 0 (Sapogenins)
RN - 0 (Saponins)
RN - 0 (Triterpenes)
RN - 7X05537I17 (medicagenic acid)
RN - 9035-51-2 (Cytochrome P-450 Enzyme System)
RN - EC 5.4.- (Intramolecular Transferases)
RN - EC 5.4.99.- (2,3-oxidosqualene-beta-amyrin-cyclase)
SB - IM
MH - Base Sequence
MH - Cytochrome P-450 Enzyme System/*genetics/metabolism
MH - Gene Expression Regulation, Plant
MH - Intramolecular Transferases/*genetics/metabolism
MH - Medicago/genetics/*metabolism
MH - Medicago sativa/genetics/metabolism
MH - Medicago truncatula/genetics/metabolism
MH - Molecular Sequence Data
MH - Organ Specificity
MH - Plant Leaves/genetics/metabolism
MH - Plant Proteins/genetics/metabolism
MH - Plant Roots/genetics/metabolism
MH - Sapogenins/*metabolism
MH - Saponins/*metabolism
MH - Sequence Analysis, DNA
MH - Triterpenes/metabolism
OTO - NOTNLM
OT - Medicago arborea
OT - Medicago sativa (alfalfa)
OT - cytochrome P450 expression
OT - inter-specific cross
OT - sapogenin synthesis
OT - triterpene saponin
EDAT- 2014/11/20 06:00
MHDA- 2016/02/13 06:00
CRDT- 2014/11/20 06:00
PHST- 2014/08/08 00:00 [received]
PHST- 2014/10/09 00:00 [accepted]
PHST- 2014/11/20 06:00 [entrez]
PHST- 2014/11/20 06:00 [pubmed]
PHST- 2016/02/13 06:00 [medline]
AID - 10.1111/nph.13162 [doi]
PST - ppublish
SO - New Phytol. 2015 Apr;206(1):303-314. doi: 10.1111/nph.13162. Epub 2014 Nov 18.